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Special Design for Cas No.86849-77-6 - Ophiopogonin D Cas No.945619-74-9 – Yongjian

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Special Design for Cas No.86849-77-6 - Ophiopogonin D Cas No.945619-74-9 – Yongjian Detail:

Ophiopogon Saponin D Name

English Name: (1β,3β,25R)-3-Hydroxyspirost-5-en-1-yl 6-deoxy-α-L-mannopyranosyl-(1->2)-[β-D-xylopyranosyl-(1->3)]-6-deoxy-β-D-galactopyranoside

Bioactivity of Ophiopogon Japonicus Saponin D

Description: Ophiopogon D is a rare natural C29 steroidal glycoside isolated from the tuber of Ophiopogon japonicus. Ophiopogonin D is a CYP2J3 inducer that increases CYP2J2 / eets and PPAR in human umbilical vein endothelial cells (HUVECs) α The expression of Ang II significantly inhibited Ang II induced NF- κ B nuclear translocation, I κ B α Down regulation, intracellular Ca2 + overload and activation of proinflammatory cytokines. Ophiopogonin D has been used to treat inflammation and cardiovascular diseases for thousands of years.

Relevant Categories

Signaling pathway > > transmembrane transport > > calcium channel

Research field > > cardiovascular disease

Signaling pathway > > cell cycle / DNA damage > > PPAR

Research field > > inflammation / immunity

Target

PPARα

NF-κB

Ca2+

Reference Documents: [1]. Wang L , et al. Homo-aro-cholestane, furostane and spirostane saponins from the tubers of Ophiopogonjaponicus. Phytochemistry. 2017 Apr;136:125-132.

[2]. Huang X, et al. Ophiopogonin D and EETs ameliorate Ang II-induced inflammatory responses via activating PPARα in HUVECs. Biochem Biophys Res Commun. 2017 Aug 19;490(2):123-133.

English Alias of Ophiopogon saponin D

(1β,3β,25R)-3-Hydroxyspirost-5-en-1-yl 6-deoxy-α-L-mannopyranosyl-(1->2)-[β-D-xylopyranosyl-(1->3)]-6-deoxy-β-D-galactopyranoside β-D-Galactopyranoside, (1β,3β,25R)-3-hydroxyspirost-5-en-1-yl O-6-deoxy-α-L-mannopyranosyl-(1->2)-O-[β-D-xylopyranosyl-(1->3)]-6-deoxy-

(2S,3R,4R,5R,6S)-2-(((2R,3R,4S,5S,6R)-5-hydroxy-2-(((4R,5′R,6R,6aR,6bS,8aS,8bR,9S,10R,11aS,12aS,12bS)-4-hydroxy-5′,6a,8a,9-tetramethyl-1,3,3′,4,4′,5,5′,6,6a,6b,6′,7,8,8a,8b,9,11a,12,12a,12b-icosahydrospiro[naphtho[2',1':4,5]indeno[2,1-b]furan-10,2′-pyran]-6-yl)oxy)-6-methyl-4-(((2S,3R,4S,5R)-3,4,5-trihydroxytetrahydro-2H-pyran-2-yl)oxy)tetrahydro-2H-pyran-3-yl)oxy)-6-methyltetrahydro-2H-pyran-3,4,5-triol

Ophiopogonin D

Deacetylophiopogonin C


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Special Design for Cas No.86849-77-6 - Ophiopogonin D Cas No.945619-74-9 –  Yongjian detail pictures

Special Design for Cas No.86849-77-6 - Ophiopogonin D Cas No.945619-74-9 –  Yongjian detail pictures


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Our organization insists all along the quality policy of "product quality is base of business survival; purchaser gratification is the staring point and ending of an business; persistent improvement is eternal pursuit of staff" as well as the consistent purpose of "reputation 1st, purchaser first" for Special Design for Cas No.86849-77-6 - Ophiopogonin D Cas No.945619-74-9 – Yongjian , The product will supply to all over the world, such as: Chile, Swiss, Mexico, Upon today, we have customers from all over the world, including USA, Russia, Spain, Italy, Singapore, Malaysia, Thailand, Poland, Iran and Iraq. The mission of our company is to provide the highest quality products with best price. We are looking forward to doing business with you!
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    5 Stars By Gill from Philippines - 2018.09.21 11:44
    This company conforms to the market requirement and joins in the market competition by its high quality product, this is an enterprise that have Chinese spirit.
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