Lihlahisoa

Naringin ke aglycone ea naringin 'me ke ea dihydroflavonoids.E na le mesebetsi ea antibacterial, anti-inflammatory, free radical scavenging, antioxidant, khohlela le expectorant, mali a theola lipid, anti-cancer, anti-tumor, antispasmodic le cholagogic, thibelo le phekolo ea mafu a sebete, ho thibela platelet coagulation, anti atherosclerosis le joalo-joalo.E ka sebelisoa haholo meriana, lijo le masimo a mang.

Antibacterial
E na le phello e matla ea antibacterial ho Staphylococcus aureus, Escherichia coli, letšollo le bacillus ea typhoid.Naringin e boetse e na le phello ho li-fungus.Ho fafatsa 1000ppm ho raese ho ka fokotsa tšoaetso ea Magnaporthe grisea ka 40-90%, 'me ha e na chefo ho batho le liphoofolong.

Antiinflammatory
Likhoto li ne li kenngoa ka intraperitoneally ka 20mg / kg letsatsi le leng le le leng, e leng se ileng sa thibela haholo ts'ebetso ea ho ruruha e bakoang ke ho kenngoa ha bolo ea boea.Galatia le ba bang.Ho fumanoe hore sehlopha se seng le se seng sa litekanyetso tsa naringin se na le phello e khahlanong le ho ruruha ka teko ea letlapa la tsebe ea mouse, 'me phello e khahlanong le ho ruruha e ile ea eketseha ka keketseho ea lethal dose.Sekhahla sa thibelo ea sehlopha se phahameng sa tekanyo e ne e le 30.67% ka phapang ea botenya le 38% ka phapang ea boima ba 'mele.[4] Feng Baomin et al.E kentse karolo ea 3 ea dermatitis ho litoeba ka mokhoa oa DNFB, ebe e fana ka naringin ka molomo bakeng sa matsatsi a 2 ~ 8 ho shebella litekanyetso tsa thibelo ea mohato oa hang-hang (IPR), mohato oa morao (LPR) le ultra late phase (VLPR).Naringin e ka thibela ka nepo edema ea tsebe ea IPR le VLPR, 'me e na le boleng bo itseng ba nts'etsopele ea anti-inflammatory.

Taolo ea 'mele oa ho itšireletsa mafung
Naringin e boloka tekanyo e loketseng ea khatello ea oxidative ka nako e itseng le libaka tse itseng ka ho laola phallo ea lielektrone ho mitochondria.Ka hona, ts'ebetso ea immunomodulatory ea naringin e fapane le e tloaelehileng e ntlafatsang 'mele ea ho itšireletsa mafung kapa li-immunosuppressants.Tšobotsi ea eona ke hore e ka tsosolosa boemo bo sa tsitsang ba ho itšireletsa mafung (boemo ba pathological) ho boemo bo haufi le bo tloaelehileng ba ho itšireletsa mafung (boemo ba 'mele), Ho e-na le ho ntlafatsa kapa ho thibela karabelo ea 'mele ea ho itšireletsa mafung unilaterally.

Taolo ea basali ea ho ilela khoeli
Naringin e na le ts'ebetso e ts'oanang le lithethefatsi tse seng tsa steroidal tse thibelang ho ruruha.E ka fokotsa tlhahiso ea prostaglandin PGE2 ka ho thibela cyclooxygenase Cox, le ho bapala karolo ea antipyretic, analgesic le ho fokotsa ho ruruha.
Ho ipapisitsoe le phello ea estrogen joalo ka naringin, naringin e ka sebelisoa bakeng sa kalafo ea estrogen ho basali ba postmenopausal ho qoba litlamorao tse mpe tse bakoang ke ts'ebeliso ea nako e telele ea estrogen.

Liphello tsa botenya
Naringin e na le phello e hlakileng ea kalafo ho hyperlipidemia le botenya.
Naringin e ka ntlafatsa haholo k'holeseterole e phahameng ea plasma, mahloriso a TG (triglyceride) le mafura a mafura a mahala ho likhoto tse nonneng.Ho ile ha fumanoa hore naringin e ka khona ho laola monocyte peroxisome proliferator activated receptor in high-fat model likhoto δ, Fokotsa boemo ba lipids maling.
Ka liteko tsa bongaka, ho ile ha fumanoa hore bakuli ba nang le hypercholesterolemia ba nka capsule e le 'ngoe e nang le 400mg naringin letsatsi le leng le le leng bakeng sa libeke tse 8.Mekhahlelo ea TC le LDL cholesterol plasma e fokotsehile, empa likhakanyo tsa TG le HDL cholesterol ha lia fetoha haholo.
Qetellong, naringin e ka ntlafatsa hyperlipidemia, e netefalitsoeng hantle litekong tsa liphoofolo le litekong tsa meriana.

Ho tlosa li-radicals tsa mahala le antioxidation
DPPH (dibenzo bitter acyl radical) ke radical ea mahala e tsitsitseng.Bokhoni ba eona ba ho qhekella li-radicals tsa mahala bo ka hlahlojoa ke 517 nm absorbance attenuation.[6] Kroyer o ithutile phello ea antioxidant ea naringin ka liteko mme a tiisa hore naringin e na le phello ea antioxidant.[7] Zhang Haide et al.Lekola ts'ebetso ea lipid peroxidation ea LDL ka colorimetry le bokhoni ba ho thibela phetoho ea oxidative ea LDL.Naringin haholo-holo e chelate Cu2 + ka lihlopha tsa eona tsa 3-hydroxyl le 4-carbonyl, kapa e fana ka proton le free radical neutralization, kapa e sireletsa LDL ho lipid peroxidation ka ho itšehla thajana.Zhang Haide le ba bang ba fumane hore naringin e na le phello e ntle ea mahala ea ho senya ka mokhoa oa DPPH.Phello ea mahala ea radical scavenging e ka bonoa ke hydrogen oxidation ea naringin ka boeona.[8] Peng Shuhui et al.E sebelisitse mohlala oa liteko oa leseli la riboflavin (IR) - nitrotetrazolium chloride (NBT) - spectrophotometry ho paka hore naringin e na le phello e hlakileng ea ho senya mefuta ea oksijene e sebetsang ea O2 - e matla ho feta ea ascorbic acid taolong e ntle.Liphetho tsa liteko tsa liphoofolo li bontšitse hore naringin e na le phello e matla ea ho thibela lipid peroxidation bokong ba mouse, pelo le sebete, mme e ka ntlafatsa haholo ts'ebetso ea superoxide dismutase (SOD) maling a toeba.

Tšireletso ea Pelo
Naringin le naringin li ka eketsa ts'ebetso ea acetaldehyde reductase (ADH) le acetaldehyde dehydrogenase (ALDH), ea fokotsa litaba tsa triglycerides ka har'a sebete le k'holeseterole e felletseng maling le sebeteng, ea eketsa litaba tsa high density lipoprotein cholesterol (HDLC), eketsa karo-karolelano. ea HDLC ho kakaretso ea k'holeseterole, le ho fokotsa index ea atherogenic ka nako e le 'ngoe, Naringin e ka khothalletsa ho tsamaisoa ha k'holeseterole ho tloha plasma ho ea sebeteng, secretion ea bile le excretion, le ho thibela phetoho ea HDL ho VLDL kapa LDL.Ka hona, naringin e ka fokotsa kotsi ea arteriosclerosis le lefu la pelo.Naringin e ka fokotsa litaba tsa cholesterol e felletseng ka plasma le ho matlafatsa metabolism ea eona.

Phello ea Hypolipidemic
Zhang Haide et al.K'holeseterole e lekiloeng ea serum (TC), low density lipoprotein cholesterol (LDL-C), plasma high density lipoprotein cholesterol (HDL-C), triglyceride (TG) le lintho tse ling tsa litoeba ka mor'a tsamaiso ea methapo ka liteko tsa liphoofoloLiphetho li bontšitse hore naringin e ka fokotsa haholo. serum TC, TG le LDL-C mme e batla e eketsa serum ea HDL-C ka tekanyo e itseng, e leng se bontšang hore naringin e bile le phello ea ho fokotsa lipid ea mali ho litoeba.[

Mosebetsi oa Antitumor
Naringin e ka laola ts'ebetso ea 'mele ea ho itšireletsa mafung le ho thibela ho hōla ha hlahala.Naringin e na le ts'ebetso ho rat leukemia L1210 le sarcoma.Liphetho li bonts'itse hore karo-karolelano ea boima ba 'mele ea thymus / boima ba litoeba e eketsehile kamora tsamaiso ea molomo ea naringin, e bonts'a hore naringin e ka ntlafatsa ts'ebetso ea 'mele ea ho itšireletsa mafung.Naringin e ka laola boemo ba T lymphocyte, ea lokisa bofokoli ba bobeli ba 'mele bo bakoang ke hlahala kapa radiotherapy le chemotherapy, le ho ntlafatsa phello ea polao ea lisele tsa mofetše.Ho tlalehoa hore naringin e ka eketsa boima ba thymus ho litoeba tse nang le mofetše oa ascites, e fana ka maikutlo a hore e ka ntlafatsa ts'ebetso ea 'mele ea ho itšireletsa mafung le ho bokella matla a eona a ka hare a khahlanong le mofetše.Ho ile ha fumanoa hore pomelo peel extract e na le phello e thibelang ho S180 sarcoma, 'me sekhahla sa thibelo ea tumor e ne e le 29.7%.

Antispasmodic le cholagogic
E na le phello e matla ho flavonoids.Naringin e boetse e na le phello e matla ho eketsa tlhahiso ea bile ea liphoofolo tsa liteko.

Phello ea Antitussive le Expectorant
Ho sebelisa phenol red e le sesupo sa phello ea ho felisa mafu, teko e bontša hore naringin e na le khohlela e matla le phello ea expectorant.

Kopo ea Clinical
E sebelisoa ho phekola tšoaetso ea baktheria, sedative le lithethefatsi tsa anticancer.
Foromo ea litekanyetso tsa kopo: suppository, lotion, ente, letlapa, capsule, joalo-joalo.