Platycodin D CAS No. 58479-68-8
Boitsebiso ba Bohlokoa
Mohloli oa tlhahiso:Platycodon grandiflorum (Jacq.) A.DC.Metso e omileng.
Mokhoa oa ho lemoha:HPLC ≥ 98%.
Litlhaloso:20mg, 50mg, 100mg, 500mg, 1g (e ka pakoa ho latela litlhoko tsa bareki).
Sebopeho:Ke phofo e tšoeu ea kristale.
Morero:E sebedisetsoa ho tseba litaba.
Tahlehelo ha o omisa:≤ 2%
Bohloeki:95%, 98%, 99%
Mokhoa oa Tlhahlobo:HPLC-DAD ＾ kapa / le＾ HPLC-ELSD
Mekhoa ea ho tsebahatsa:mass spectrometry (boima), nuclear magnetic resonance (NMR)
Polokelo:e tiisitsoe ebile e sirelelitsoe khanyeng, - 20 ℃.
Mehato ya tlhokomelo:Sehlahisoa sena se lokela ho bolokoa ka mocheso o tlase le ho omella.Lihlahisoa tse khethehileng li lokela ho bolokoa tlas'a naetrojene.Haeba e sa bolokoe nako e telele, litaba li tla fokotseha.
Ho nepahala:lilemo tse 2
E ka finyella palo e kholo ea litlhoko tse ka holimo ho tekanyo ea gram.Ka kopo, sheba lintlha.
Bioactivity ea Platycodin D
Tlhaloso:platycodin D ke motsoako oa saponin o arohaneng le lehlaka la lamunu, e leng AMPK α E na le ts'ebetso e khahlanong le botenya.
Tse amanangClihlopha:tsela ya matshwao > > epigenetics > > AMPK
Tsela ea matšoao>> PI3K / Akt / mTOR tsela ea lets'oao>> AMPK
Sebaka sa lipatlisiso > > mafu a metabolism
Sepheo:AMPK α [1]
Litšupiso:[1] Kim HL, le ba bang.Platycodin D, moqapi oa buka oa AMP-activated protein kinase, o fokotsa botenya ho litoeba tsa db/db ka taolo ea adipogenesis le thermogenesis.Phytomedicine.2019 Jan;52:254-263 .
Thepa ea Physicochemical ea Platycodin D
Tekano:1.6 ± 0.1 g / cm3
Foromo ea molek'hule:c57h92o28
Boima ba molek'hule:1225.324
Boima bo nepahetseng:1224.577515
PSA:453.28000
LogP:-0.69
Lenane la Refractive:1.659
