Synephrine
Tšebeliso ea Synephrine
Synephrine (oxedrine) e tsoa ho limela tsa citrus α- Adrenergic le β- Adrenergic agonists li na le ho tšoana ho nang le kutloelo-bohloko le sebopeho le ephedra le ephedrine alkaloids.
Lebitso la Synephrine
Lebitso la Senyesemane: synephrine
Lebitso la Sechaena: deoxyepinephrine |simfoni |DL deoxyepinephrine |1-p-hydroxyphenyl-2-methylaminoethanol |cinephrine |1 - (4-hydroxyphenyl) - 2 - (methylamino) ethanol
Bioactivity ea Synephrine
Tlhaloso: synephrine (oxedrine) e tsoa ho limela tsa citrus α- Adrenergic le β- Adrenergic agonists li na le ho tšoana ho nang le kutloelo-bohloko le sebopeho le ephedra le ephedrine alkaloids.
Lihlopha tse amehang: α- adrenergic le β-adrenergic[1]
Thutong ea Vivo: adrenaline (1mg / kg; gavage ea molomo; e tšoarellang matsatsi a 8; likhoto tsa PVL le BDL) e ntlafalitse haholo boemo ba hyperkinetic ba likhoto tsa PVL le BDL.PVL le likhoto tsa BDL li fokotse haholo khatello ea methapo ea portal, phallo ea mali ea phallo ea mali le index ea pelo, athe kalafo ea adrenaline e ile ea eketsa khatello ea methapo ea methapo le systemic le portal vein vascular resistance [2].Mohlala oa liphoofolo: Likhoto tse nang le portal vein ligation (PVL) kapa bile duct ligation (BDL) [2] tekanyo: 1 mg / kg lihora tse ling le tse ling tsa 12: oral gavage;Liphetho ka letsatsi la 8: likhoto tsa PVL le BDL li ne li fokotsehile haholo khatello ea methapo ea portal, phallo ea mali ea lekala ea portal le index ea pelo, le ho eketseha ha khatello ea methapo ea methapo le ho hanyetsa tsamaiso le methapo ea portal.
Litšupiso: 1] Thomas JE, et al.STEMI ho monna ea lilemo li 24 ka mor'a tšebeliso ea lijo tse nang le synephrine e nang le phepo e nepahetseng: tlaleho ea nyeoe le tlhahlobo ea lingoliloeng.Tex Heart Inst J. 2009;36(6):586-90.
[2].Huang YT, le ba bang.Liphello tsa Hemodynamic tsa phekolo ea synephrine ho likhoto tsa portal hypertensive.Jpn J Pharmacol.2001 Hlakola;85(2):183-8.
Lintho tsa Physicochemical of Simephrine
Boima: 1.2 ± 0.1 g / cm3
Ntho e Belang: 341.1 ± 27.0 ° C ho 760 mmHg
Sebaka se qhibilihang: 187 ° C (Dec.) (hote.)
Foromo ea molek'hule: C9H13NO2
Boima ba 'mele: 167.205
Sebaka se benyang: 163.4 ± 14.3 ° C
Boima bo nepahetseng: 167.094635
PSA: 52.49000
LogP:-0.03
Ponahalo: ho tloha bosoeu ho isa ho phofo ea beige
Khatello ea Mouoane: 0.0 ± 0.8 mmHg ho 25 ° C
Index ea Refractive: 1.572
Maemo a polokelo: Sehlahisoa sena se lokela ho koaloa le ho bolokoa.
Lintlha tsa Tšireletseho tsa Synflynn
Setšoantšo: ghs07
Lesupa la lentsoe: temoso
Polelo ea kotsi: h315-h319-h335
Polelo ea temoso: p261-p305 + P351 + P338
Lisebelisoa tsa ho itšireletsa: mofuta oa mask oa lerole N95 (US);Litšiea tsa mahlo;Liatlana
Khoutu ea kotsi (Europe): Xi: iritant;
Polelo ea kotsi (Yuropa): R36 / 37/38
Polelo ea polokeho (Europe): s26-s36
Khoutu ea lipalangoang ea thepa e kotsi: nonh bakeng sa mefuta eohle ea lipalangoang
Nomoro ea RTECS: do7350000
Meetlo Code: 2922199090
Tokisetso ea Synephrine
Liphetho tsa citrus aurantium L.
Mekhoa ea Synephrine
Khoutu ya Dikgetho: 29225090
Tlhaloso ea Sechaena: 29225090 Tse ling tsa amino alcohol phenols, amino acid phenols le metsoako e meng ea amino e nang le oksijene Sekhahla sa VAT: 17.0% Sekhahla sa phokotso ea Lekhetho: 13.0% Maemo a taolo: ab.Litefiso tsa MFN: 6.5% Litefiso tse akaretsang: 30.0%
Declaration Elements: lebitso la sehlahisoa, sebopeho, dikahare, morero, chroma ea ethanolamine le letsoai la eona li tla tlalehoa, 'me ho tla tlalehoa sephutheloana sa ethanolamine le letsoai la eona.
Maemo a tlhokomelo: Foromo ea tumello ea lekhetho bakeng sa Thepa e Kenang B. Foromo ea tumello ea thepa bakeng sa thepa e tsoang kantle.
Inspection And Quarantine: R. tlhokomelo ea bohloeki le tlhahlobo ea lijo tse tsoang kantle ho naha S. tlhokomelo ea bohloeki le tlhahlobo ea lijo tse romelloang kantle ho naha.
Kakaretso:2922509090.tse ling tsa amino-alcohol-phenols, amino-acid-phenols le metsoako e meng ea amino e nang le ts'ebetso ea oksijene.VAT:17.0%.Sekhahla sa phokotso ea lekhetho:13.0%..Litefiso tsa MFN: 6.5%.Litefiso tse akaretsang: 30.0%
Lingoliloeng tsa Synephrine
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Senyesemane Alias Of Synephrine
Synefrin
Simpatol
EINECS 202-300-9
4-[(1R)-1-Hydroxy-2-(methylamino)ethyl]phenol
(-) -Oxedrine
Oxedrine
(-)-Sympatol
(R) -4-(1-hydroxy-2-(methylamino)ethyl)phenol
1-(4-Hydroxyphenyl) -2-methylaminoethanol
Synephrin
Ethaphene
Analeptin
Simpalon
(-) -Synephrine
Benzenemethanol, 4-hydroxy-α--[(methylamino)methyl]-, (αR)-
Synephrine
MFCD00002370
D-Synephrine
(-) -4-hydroxy-α--[(methylamino)methyl]benzenemethanol
Sympathol
Pendrine
(-)-p-hydroxy-α--[(methylamino)methyl]benzyl joala
