Vitexin;Apigenin8-C-glucoside CAS No. 3681-93-4
Boitsebiso ba Bohlokoa
Leetsi:apigenin8-c-glucoside
Lebitso la lik'hemik'hale:8- β- D-glucopyranosyl-5,7-dihydroxy-2-(4-hydroxyphenyl) -4H-1-benzopyran-4-one
Foromo ea molek'hule:c21h20o10 pososelo ea molao: C1 = CC (= CC = C1C2 = CC (= O) C3 = C (O2) C (= C (C = C3O) o) C4C (C (C (O4) co) o) o) o
Boima ba molek'hule:432.3775
Nomoro ea CAS:3681-93-4
Thepa ea 'Mele le ea Lik'hemik'hale
Ponahalo:phofo e tshehla
Mohloli:Craeagus pinnatifida, semela sa Rosaceae, se na le litholoana tse omeletseng le tse holileng.
Kopo
Ka hona, lisebelisoa tse tala tsa makhasi a hloekileng a Vitex le peo ea Vitex li batla li haella, 'me makhasi a bokelitsoeng a Vitex a sebelisoa ha e le hantle ho qhala le ho hloekisa oli ea Vitex, e lebisang baetsi ba lihlahisoa tsa semela ho lahla metheo le ho ntša Vitexin.Ho e-na le hoo, ba sebelisa makhasi a hawthorn ho ntša Vitexin, ho ntša Vitexin ho tsoa ho flavonoids eohle ea Makhasi a Hawthorn ka ho ntša, ho arohana, ho hloekisa le mekhoa e meng, 'me qetellong ba etse litokisetso tse omisitsoeng ka leqhoa.
Vitexin e sebelisoa haholo ho phekola mafu a pelo.Ho hloeka ha Vitexin ka kakaretso ho hlokahala hore e be> 98% (HPLC).Vitexin bakeng sa ente e sebelisitsoe meriana ea bongaka.Mesebetsi e ka sehloohong ea Vitexin ke ho khothalletsa phallo ea mali le ho tlosa stasis ea mali, ho laola qi le ho fokotsa sekhahla.E sebelisetsoa ho thibela sefuba ho bakoang ke stasis ea mali.Matšoao a kenyelletsa ho tiea ha sefuba, ho bipetsana, ho tsikitlanya sebakeng sa precordial, ho otla ha pelo, ho lebala, ho tsekela le tinnitus.Lefu la pelo, angina pectoris, hyperlipidemia, phepelo e sa lekaneng ea mali ea methapo ea pelo le matšoao a mang.
Mafu a pelo le cerebrovascular ke mafu a atileng haholo ho batho, 'me a fetohile sesosa se seholo sa lefu lefatšeng.Ho latela likhakanyo tsa WHO, mafu a pelo le methapo ea mali a baka bonyane mafu a limilione tse 12 lefatšeng ka bophara selemo se seng le se seng, ’me a fetohile sera sa pele sa bophelo ba batho.Boemo bo phahameng le ho shoa ha mafu a pelo le methapo li tataisa tataiso ea lithethefatsi R & D le tlhahiso.Lithethefatsi tsa pelo le cerebrovascular ke tse 4 ho tse 10 tse rekisoang ka ho fetisisa lefatšeng ka 2005. Ho na le mefuta e mengata ea meriana ea machaena ea patent bakeng sa kalafo ea mafu a pelo le methapo, empa ha ho na mefuta e fetang e meraro (Fuzheng Ningxin, Wentong e nkhang hamonate). , ho khothalletsa ho potoloha ha mali le ho tlosa stasis ea mali).Ho tloha boemong ba thekiso 'marakeng oa mabenkele, Vitexin le lithethefatsi tse ling bakeng sa ho khothalletsa ho potoloha ha mali le ho tlosa stasis ea mali ho na le boemo bo botle ba ho rekisa.Ke e 'ngoe ea lithethefatsi tse nang le khōlo e potlakileng ka ho fetisisa.Mmaraka o hola ka potlako, o na le bokhoni bo boholo, bokhoni bo boholo ba mebaraka le sebaka se pharaletseng sa tlholisano.
Vitexin hape ke karolo ea tlhaho ea lithethefatsi bakeng sa anti-cancer le anti-tumor.Foreign Diaz e tlaleha hore li-flavonoids tse fumanoeng ho Vitex negundo, tse kang Vitexin, li bontšitse cytotoxicity e ngata ho lisele tsa kankere ea batho ka bioassay;Massateru et al.Ho fumanoe hore bauhinin e thibela kholo ea lisele tsa kankere ea matšoafo ea motho (PC-12) le lisele tsa kankere ea mala a motho (HCT116) tekong ea MTT.
Baetsi ba bangata ba ho ntša limela ba hlahisa lihlahisoa tsa limela tsa Vitexin.Ntle le tlhahiso ea Vitexin, joalo ka tlhahiso ea Vitexin le hawthorn extract, kaofela ha tsona li hlahisa Vitexin e le index ea likarolo tse sebetsang, 'me lihlahisoa li boetse li rekisoa ho bareki ba nang le Vitexin joalo ka index.Lenane la litaba tsa Vitexin liqotsong tsa Vitex le hawthorn ha e le hantle ke hoo e ka bang 5%.
Ke lumela hore u boetse u bone litlaleho tse tšoanang mabapi le anti-cancer le anti-cancer ea Hawthorn: liphuputso tsa morao tjena li fumane hore Hawthorn e na le motsoako o bitsoang Vitexin, o nang le phello ea anti-cancer.Nitrosamine le aflatoxin li ka baka ho hlaha kapa ho mpefala ha mofetše oa tšilo ea lijo.Liphuputso tsa liteko li bontša hore hawthorn e ntšitsoeng e ke ke ea thibela feela motsoako oa nitrosamine, empa hape e thibela phello ea carcinogenic ea aflatoxin.Ka hona, batho ba kotsing e kholo ea kankere ea mala ba lokela ho ja hawthorn hangata.Bakeng sa bakuli ba nang le kankere, hawthorn le raese li ka boela tsa sebelisoa ho pheha motoho hammoho tabeng ea dyspepsia, e ke keng ea thusa feela tšilo ea lijo, empa hape e phetha karolo e thusang ho thibela kankere.
Lik'hemik'hale tsa Vitexin tse Hawthorn li tlase haholo ho feta tsa Vitexin, empa hobane ke batho ba fokolang ba hlileng ba tsebang le ho utloisisa Vitexin ho rua, phello e khahlanong le mofetše le e khahlanong le mofetše ea Vitexin e notletsoe lithabeng!