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Top Suppliers Cas No.29388-59-8 - Fraxin; Paviin; Fraxoside; Fraxetol- 8-glucoside CAS No.524-30-1 – Yongjian

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Top Suppliers Cas No.29388-59-8 - Fraxin; Paviin; Fraxoside; Fraxetol- 8-glucoside CAS No.524-30-1 – Yongjian Detail:

Essential Information

CAS No.: 524-30-1 [1]

EINECS No.: 208-355-5

Molecular Formula: c16h18o10

Molecular Weight: 370.3081

Molecular Structure: (Figure 1)

Properties: Light yellow acicular crystal or flake crystal.

Density: 1.634g/cm3

Boiling Point: 722.2 ° C at 760 mmHg

Flash Point: 267 ° C

Steam Pressure: 6.87e-22mmhg at 25 ° C

Bioactivity of Fraxin

Description: Fraxin can be isolated from Acer tegmentosum, F. ornus and a. hippocastanum. It is a glycoside of fraxine [1] and has antioxidant, anti-inflammatory and anti metastasis activities. Fraxin exhibits antioxidant activity by inhibiting cyclic adenylate phosphodiesterase [2].

Target: cyclo AMP phosphodiesterase enzyme [2]

In Vitro Study: Fraxin (100 μ M) It has no cytotoxicity to Hep G2 cells. Fraxin at non cytotoxic concentrations significantly reduced t-BHP induced ROS production in a dose-dependent manner [1]. Fraxin (0.5 mm) can scavenge free radicals at high concentration and has cytoprotective effect on H2O2 mediated oxidative stress [2].

In vivo study: Fraxin (50 mg / kg, PO) significantly blocked CCl4 induced elevation of ALT and AST. Fraxin (10 and 50 mg / kg, PO) significantly reduced GSSG levels (1.7 ± 0.3 and 1.5 ± 0.2 nm / g liver, respectively) compared with GSSG levels in the CCl4 treated group

Reference:. Fraxin (50 mg/kg, p.o.) significantly blocks the CCl4-induced elevation of ALT and AST. Fraxin (10 and 50 mg/kg, p.o.) significantly reduces the GSSG levels (1.7±0.3 and 1.5±0.2 nM/g liver, respectively) compared with the GSSG levels of the CCl4-treated group[1].

[2]. Whang WK, et al. Natural compounds,fraxin and chemicals structurally related to fraxin protect cells from oxidative stress. Exp Mol Med. 2005 Oct 31;37(5):436-46.


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Top Suppliers Cas No.29388-59-8 - Fraxin; Paviin; Fraxoside; Fraxetol- 8-glucoside CAS No.524-30-1  –  Yongjian detail pictures

Top Suppliers Cas No.29388-59-8 - Fraxin; Paviin; Fraxoside; Fraxetol- 8-glucoside CAS No.524-30-1  –  Yongjian detail pictures


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We emphasize progress and introduce new solutions into the market each year for Top Suppliers Cas No.29388-59-8 - Fraxin; Paviin; Fraxoside; Fraxetol- 8-glucoside CAS No.524-30-1 – Yongjian , The product will supply to all over the world, such as: Barcelona, Amman, Suriname, With nearly 30 years' experience in business, we are confident in superior service, quality and delivery. We warmly welcome customers from all over the world to cooperate with our company for common development.
  • The sales person is professional and responsible, warm and polite, we had a pleasant conversation and no language barriers on communication.
    5 Stars By Klemen Hrovat from Cannes - 2018.11.28 16:25
    Wide range, good quality, reasonable prices and good service, advanced equipment, excellent talents and continuously strengthened technology forces,a nice business partner.
    5 Stars By Bertha from Nepal - 2017.09.30 16:36
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