1,2,4-Trihydroxyanthraquinone;purpurin
Ukusetyenziswa kwePurpurin
I-Purpurin yinto yendalo ye-anthraquinone evela kwi-Rubia tinctorum L. I-Purpurin ine-antidepressant efana nemiphumo.
Igama le Purpurin
Igama lesiNgesi: purpurin
Igama lesiTshayina:
Violin |1,2,4-trihydroxyanthraquinone |hydroxyalizarin |1,2,4-trihydroxyanthraquinone |IViolin ebomvu / 1,2,4-trihydroxyanthraquinone |Ivayolin eBomvu
I-Bioactivity yePurpurin
Inkcazo: i-purpurin yinto yendalo ye-anthraquinone evela kwi-Rubia tinctorum L. I-Purpurin ine-antidepressant efana nemiphumo.
Iindidi eziyeleleneyo: indlela yesignali > > enye > > enye
Ummandla wophando > > izifo zemithambo-luvo
KwiSifundo seVivo: isiphumo se-purpurin (ngomlomo; 2,6,18mg / kg, iiveki ze-3) kumadoda akhulileyo e-C57BL / 6J iimpuku (iiveki ze-6-7) ukuziphatha kunye noxinzelelo lwe-axis reactivity kuvelisa i-dose-dependent antidepressant efana neziphumo. [1].
Iimbekiselo: [1] Ma L, et al.I-Purpurin yenza i-antidepressant-efana nemiphumo yokuziphatha kunye noxinzelelo lwe-axis reactivity: ubungqina bokubandakanyeka kwe-serotonergic.I-Psychopharmacology (Berl).2020 Mar;237(3):887-899.
Iimpawu zePhysicochemical yePurpurin
Ubuninzi: 1.7 ± 0.1 g / cm3
Indawo yokuBilisa: 525.1 ± 45.0 ° C kwi-760 mmHg
Indawo yokunyibilika: 253-256 º C (lit.)
Ifomula yemolekyuli: c14h8o5
Ubunzima beMolekyuli: 256.210
Upholeko lweNdawo: 285.4 ± 25.2 ° C
Ubunzima obuchanekileyo: 256.037170
PSA: 94.83000
IlogP:4.60
Imbonakalo: Umgubo
Uxinzelelo lomphunga: 0.0 ± 1.4 mmHg ku-25 ° C
Refractive Index: 1.773
Iimeko zokugcina: Le mveliso kufuneka ivalwe kwindawo eyomileyo nemnyama yokugcina.
Ulwakhiwo lweemolekyuli
1. Isalathisi se-Molar refractive: 64.31
2. Umthamo weMolar (m3 / mol): 154.3
3. Umthamo othile we-Isotonic (90.2k): 480.4
4. Uxinzelelo lomphezulu (dyne / cm): 93.9
5. I-polarizability (10-24cm3): 25.49
Ulwazi lokhuseleko lwePurpurin
Igama loMqondiso: isilumkiso
Inkcazo yengozi: h315-h319-h335
Ingxelo yesilumkiso: p261-p305 + P351 + P338
Izixhobo zoKhuseleko zoMntu: uhlobo lwemaski yothuli i-N95 (US);Izikhuselo zamehlo;Iiglavu
Ikhowudi Yengozi (eYurophu): Xi: iritant;
Ingxelo yoMngcipheko (eYurophu): R36 / 37 / 38
Ingxelo yoKhuseleko (eYurophu): S26;S36
IKhowudi yezoThutho yempahla eyingozi: nonh kuzo zonke iindlela zothutho
Wgk eJamani: 3
Inombolo ye-RTECS: cb8200000
Ikhowudi yeCustoms: 2914690090
Purpurin Customs
Ikhowudi yeCustoms: 2914690090
Isishwankathelo saseTshayina: 2914690090 ezinye iiquinone Ixabiso lerhafu eyongeziweyo: 17.0%, isaphulelo serhafu: 9.0%, iimeko zolawulo: akukho ntlawulo yeMFN: 5.5%, intlawulo eqhelekileyo: 30.0%
Ushwankathelo:2914690090 ezinye iiquinones
Uncwadi
Iimpawu zesakhiwo kunye ne-optical ye-Purpurin yeeseli zelanga ezenziwe ngedayi.
I-Spectrochim.Acta.A. Mol.Biomol.I-Spectrosc.149 , 997-1008, (2015)
Kulo msebenzi, sichaze uphando oludityanisiweyo lokulinga kunye nethiyori malunga nesakhiwo semolekyuli, i-vibrational spectra kunye nohlalutyo lweHomo-Lumo lwePurpurin kunye neTiO2 / Purpurin.Iijometri, i-elektroniki ...
Ukukhuselwa kwi-bacterial mutagenicity ye-heterocyclic amines nge-purpurin, i-pigment yendalo ye-anthraquinone.
Mutat.Res.444(2), 451-61, (1999)
I-Purpurin (1,2,4-trihydroxy-9,10-anthraquinone) yindalo ye-anthraquinone pigment efumaneka kwiindidi ze-madder root.Sifumene ukuba ubukho be-purpurin kwi-esile ye-mutagenicity ye-bacterial ...
Ubuthi kunye ne-tumorigenicity ye-purpurin, i-hydroxanthraquinone yendalo kwiigundane: ukufakwa kwe-neoplasms yesinyi.
Umhlaza Lett.102(1-2), 193-8, (1996)
Ubuthi obungapheliyo kunye ne-tumorigenicity ye-purpurin, i-hydroxyanthraquinone yendalo, yavavanywa kumaqela amabini eempuku ze-F344 zamadoda.Elinye iqela lanikwa ukutya okusisiseko okuxutywe nepurpurin kwindawo yoxinaniso o...
Englisah Alias Of Purpurin
I-EINECS 201-359-8
I-Verantin
Purpurin
I-1,2,4-Trihydroxy-9,10-anthracenedione
I. Ubomvu beNdalo 16
obomvu bendalo 161,2,4-Trihydroxy-9,10-anthraquinone
9,10-Anthracenedione, 1,2,4-trihydroxy-
Purpurine
I-CI Yendalo Ebomvu 8
I-1,2,4-trihydroxyanthracene-9,10-dione
I-1,2,4-trishydroxy-9,10-anthraquinone
1,2,4-Trihydroxyanthraquinone
Umsi uBrown G
MFCD00001203
Hydroxylizaric acid
