Ibenzoylpaeoniflorin
Ukucaciswa kweMveliso
EqhelekileyoIgama: benzoyl paeoniflorin
Inombolo yeCAS:38642-49-8
Igama lesiNgesi:benzoylpaeoniflorin
Ubunzima beMolekyuli:584.568
Ubuninzi:1.6 ± 0.1 g / cm3 indawo ebilayo: 742.9 ± 60.0 ° C ku-760 mmHg
Ifomula yemolekyuli:c30h32o12 indawo yokunyibilika: n / A
MSDS: n / i-flash point: 243.1 ± 26.4 ° C
Umsebenzi webhayoloji weBenzoyl paeoniflorin
Inkcazo:i-benzoylpaeoniflorin yikhompawundi yendalo, echazwe ukuba iphathe isifo senhliziyo ngokunciphisa i-apoptosis.
Iindidi ezinxulumeneyo:indlela yomqondiso > > enye > > enye
Iimveliso zendalo > > i-terpenoids kunye ne-glycosides
Indawo yophando > > isifo sentliziyo
Isalathiso:[1].Xinfeng Zhao, et al.Ukumiselwa kobungakanani kunye noBulunga beetafile ze-Liuwei Dihuang yi-HPLC–UV-MS–MS.Ijenali yeChromatographic Science, Vol.45, Septemba 2007, 549-552
[2].ZHANG Er-li, et al.Iimpembelelo ze-Benzoylpaeoniflorin kwi-apoptosis yeegundane ezineZifo ze-Coronary Heart.Ijenali yaseTshayina yoxilongo lweLabhoratri, ngo-2011-04.
Iimpawu zePhysicochemical zebenzoyl paeoniflorin
Ubuninzi:1.6 ± 0.1 g / cm3
Indawo yokuBilisa:742.9 ± 60.0 ° C kwi-760 mmHg
Ifomula yemolekyuli:C30H32O12
Ubunzima beMolekyuli:584.568
Indawo yokuflasha:243.1 ± 26.4 °
IMisa echanekileyo:584.189392
PSA:170.44000 LogP:5.55
Uxinzelelo lomphunga:0.0 ± 2.6 mmHg ku-25 ° C
Refractive Index:1.682
Igama lesiNgesi leBenzoylpaeoniflorin
{(3S,5R,6S)-1-({[(4,5-Dihydroxy-2-cyclohexen-1-yl)carbonyl]oxy}methyl)-3-[(1aR)-1H-3,4-dioxacyclobuta [cd]pentalen-1a(2H)-yloxy]-5,6-dihydroxy-4-methyl-2-oxabicyclo[2.2.1]hept-3-yl}methyl benzoate
I-2-Cyclohexene-1-carboxylic acid, 4,5-dihydroxy-, [(3S,5R,6S)-3-[(benzoyloxy)methyl]-3-[(1aR) -1H-3,4-dioxacyclobuta[cd ]pentalen-1a(2H)-yloxy]-5,6-dihydroxy-4-methyl-2-oxabicyclo[2.2.1]hept-1-yl]methyl ester
β-D-Glucopyranoside, (1aR,2S,3aR,5R,5aR,5bS) -5b-[(benzoyloxy)methyl]tetrahydro-5-hydroxy-2-methyl-2,5-methano-1H-3,4- dioxacyclobuta[cd]pentalen-1a(2H)-yl, 6-benzoate
{(1R,2S,3R,5R,6R,8S) -3-[(6-O-Benzoyl-β-D-glucopyranosyl) oxy] -6-hydroxy-8-methyl-9,10-dioxatetracyclo [4.3. 1.0.0]dec-2-yl}methyl benzoate
Jiangsu Yongjian Pharmaceutical Technology Co., Ltd
I-Jiangsu Yongjian Pharmaceutical Technology Co., Ltd., esekwe ngoMatshi ka-2012, lishishini lobugcisa obuphezulu elidibanisa i-R & D, imveliso kunye neentengiso.Isebenza ikakhulu kwimveliso, uhlengahlengiso kunye nophuhliso lwenkqubo yemveliso yamacandelo asebenzayo emveliso yendalo, izixhobo zesalathiso samayeza esintu kunye nokungcola kweziyobisi.Inkampani ifumaneka kwisiXeko sase-China se-Pharmaceutical City, kwisiXeko saseTaizhou, kwiPhondo laseJiangsu, kubandakanywa nesiseko sokuvelisa i-5000 ye-square meter kunye ne-2000 ye-square meter ye-R & D isiseko.Isebenza ikakhulu kumaziko ophando lwenzululwazi, iiyunivesithi kunye namashishini emveliso ye-decoction kwilizwe lonke.
Ukuza kuthi ga ngoku, siye savelisa ngaphezu kwe-1500 iintlobo ze-reagents zekhompawundi zendalo, kwaye sithelekisa kwaye salinganisa ngaphezu kwe-300 iintlobo zezixhobo zereferensi, ezinokuhlangabezana ngokupheleleyo neemfuno zokuhlolwa kwemihla ngemihla zamaziko ophando lwenzululwazi, iilebhu zeyunivesithi kunye namashishini okuvelisa amaqhekeza e-decoction.
Ngokusekwe kumgaqo wokholo oluhle, inkampani inethemba lokusebenzisana ngokunyanisekileyo nabathengi bethu.Injongo yethu kukusebenzela ukuphuculwa kwamayeza emveli aseTshayina.
Ubume boshishino oluluncedo lwenkampani
I-1.R & D kunye nokuthengiswa kwamayeza emveli aseTshayina kunye neemveliso zolawulo lweekhemikhali;
I-2.I-Customized Chinese amayeza e-monomer compounds ngokweempawu zabathengi
3.Uphando kumgangatho womgangatho kunye nophuhliso lwenkqubo yamayeza emveli aseTshayina (isityalo) isicatshulwa
4. Intsebenziswano yobuchwephesha, ukudluliselwa kunye nophando olutsha lweziyobisi kunye nophuhliso.
Inkonzo elungiselelweyo yemathiriyeli yereferensi yemichiza yezamayeza zesiNtu zaseTshayina
I-Jiangsu Yongjian Pharmaceutical Technology Co., Ltd. ibandakanyeka ikakhulu kuphando olusisiseko lwezinto ezisebenzayo zamayeza esintu amaTshayina ngaphezulu kweminyaka elishumi.Ukuza kuthi ga ngoku, inkampani yenze uphando olunzulu kwiintlobo ezingaphezu kwe-100 zamayeza esintu aqhelekileyo asetyenziswa eTshayina, kwaye yakhupha amawaka eekhemikhali.
Inkampani inabasebenzi abaphezulu be-R & D kunye novavanyo olugqibeleleyo kunye nezixhobo zokuhlalutya kushishino, kwaye ikhonze amakhulu amaziko ophando lwezenzululwazi.Inokukhawuleza kwaye ihlangabezane neemfuno zabathengi.
Ukwahlulwa kokungcola kweziyobisi, ukuLungisa kunye neNkonzo yoQinisekiso lweZakhiwo
Ukungcola kwiziyobisi kuhambelana ngokusondeleyo nomgangatho, ukhuseleko kunye nokuzinza kwamachiza.Ukulungiswa kunye nokuqinisekiswa kwesakhiwo sokungcola kwiziyobisi kunokusinceda siqonde iindlela zokungcola kunye nokubonelela ngesiseko sokuphucula inkqubo yokuvelisa.Ngoko ke, ukulungiswa kunye nokwahlula ukungcola kubaluleke kakhulu kuphando lweziyobisi kunye nophuhliso.
Nangona kunjalo, umxholo wokungcola kwiyeza liphantsi, umthombo ubanzi, kwaye isakhiwo sininzi sifana necandelo eliphambili.Yeyiphi itekhnoloji enokusetyenziswa ukwahlula kunye nokucoca bonke ukungcola kwichiza nganye nganye kwaye ngokukhawuleza?Zeziphi iindlela neendlela ezisetyenziswayo ukuqinisekisa ubume bobu kungcola?Obu bubunzima kunye nomngeni ojongene namacandelo amaninzi oxubo mayeza, ngakumbi amashishini axuba amayeza ezityalo kunye namayeza elungelo elilodwa lomenzi wechina.
Ngokusekwe kwiimfuno ezinjalo, inkampani iye yasungula ukwahlulwa kokungcola kweziyobisi kunye neenkonzo zokucoca.Ukuxhomekeka kwi-resonance yamagnetic yenyukliya, i-spectrometry yobunzima kunye nezinye izixhobo kunye nobuchwepheshe, inkampani inokuchonga ngokukhawuleza ukwakheka kweekhompawundi ezahluliweyo, ukuze ihlangabezane neemfuno zabathengi.
SPF Animal Experiment
Indawo yolwakhiwo yendawo yovavanyo lwezilwanyana yi-1500 square metres, kubandakanywa i-400 square metres yendawo yovavanyo yenqanaba le-SPF kunye ne-100 yeemitha zesikwere selebhu yenqanaba le-P2 yeseli.Ikhokelwe ngoosonzululwazi base China Pharmaceutical University, yenza iqela lobugcisa elingundoqo elinenani lababuyileyo.Ukubonelela ngeemodeli zezilwanyana ezikumgangatho ophezulu, uyilo lokulinga, iiprojekthi zizonke kunye nezinye iinkonzo zophando lwenzululwazi yebhayoloji, ukufundisa kunye nophuhliso lwemizimveliso.
Umda weShishini:
1. Ukutyisa izilwanyana ezincinci
2. Imodeli yezifo zezilwanyana
3. Ukunikezelwa kweprojekthi yasekholejini
4. Uvavanyo lwe-Pharmacodynamic kwi-vivo
5. Uvavanyo lwe-Pharmacokinetic
6. Inkonzo yokulinga iseli yethumba
Amandla ethu:
1. Gxininisa kwimifuniselo yokwenyani
2. Qinisekisa ngokungqongqo inkqubo
3. Utyikitye ngokungqongqo isivumelwano semfihlo
4. Ilabhoratri yeyakho ngaphandle kwamakhonkco aphakathi
5. Iqela lobugcisa lobuchwephesha liqinisekisa umgangatho wokulinga
Imekobume yovavanyo ye-SPF, ukondla umntu owabelwe ngokukhethekileyo, ukulandelela ixesha lokwenyani inkqubela yovavanyo
