Calycosin CAS No. 20575-57-9
Ulwazi oluBalulekileyo
【Igama eliqhelekileyo】Pistil isoflavone
【Igama lesiNgesi】calycosin
【Inombolo yeCAS.】 20575-57-9
【Imolekyuli Ubunzima】 284.263
【Ukuxinana】 1.4 ± 0.1 g / cm3
【Indawo yokubilisa】536.8 ± 50.0 ° C kwi-760 mmHg
【Ifomula yeemolekyuli】C16H12O5
【Indawo yokunyibilika】n / A
Ukusetyenziswa kweCalycosin
I-Calycosin yimbumba yendalo ene-antioxidant kunye ne-anti-inflammatory activities.
I-Bioactivity yeCalycosin
Inkcazo: I-Calycosin yimbumba yendalo kunye nemisebenzi ye-antioxidant kunye ne-anti-inflammatory.
Iindidi ezinxulumeneyo:
Indlela yomqondiso > > enye > > enye
Indawo yophando > > umhlaza
Iimveliso zendalo > > iiflavonoids
Isalathiso:
[1].UZhou Y, et al.I-Calycosin yenza i-apoptosis kumhlaza we-ovarian yabantu iiseli ze-SKOV3 ngokuvula i-caspases kunye neeprotheni zeentsapho ze-Bcl-2.I-Biol ye-Tumor.2015 Feb 12.
[2].UChen J, kunye nabanye.I-Calycosin kunye ne-genistein yenza ukuba i-apoptosis ingasebenzi ngokungasebenzi kwe-HOTAIR / p-Akt indlela yomqondiso kumhlaza wesifuba womntu iiseli ze-MCF-7.ISeli yePhysiol Biochem.2015;35(2):722-8.
[3].UChen J, kunye nabanye.I-Calycosin icinezela ukukhula kweeseli zomhlaza webele ngokusebenzisa umgaqo oxhomekeke ku-ERβ we-IGF-1R, i-p38 MAPK kunye ne-PI3K / Akt iindlela.I-PLoS enye.2014 Mar 11;9(3):e91245.
[4].UChen J, kunye nabanye.I-Calycosin ikhuthaza ukwanda kweeseli ze-estrogen receptor-positive ngokusebenzisa i-estrogen receptors kunye ne-ERK1 / 2 i-activation in vitro kunye ne-vivo.Umhlaza Lett.2011 Sep 28;308(2):144-51.
Iimpawu zePhysicochemical zeCalycosin
Ubuninzi:1.4 ± 0.1 g / cm3
Indawo yokubilisa:536.8 ± 50.0 ° C kwi-760 mmHg
Ifomula yemolekyuli:C16H12O5
Ubunzima bemolekyuli:284.263
Indawo yokuflasha:205.7 ± 23.6 ° C
PSA:79.90000
Ubunzima obuchanekileyo:284.068481
LogP:2.41
Imbonakalo:mhlophe ukuya kumthubi okhanyayo
Uxinzelelo lomphunga:0.0 ± 1.5 mmHg ku-25 ° C
Isalathiso seRefractive:1.669
Iimeko zokugcina:2-8 ° C
Ukunyibilika kwamanzi:I-methanol: i-soluble1mg / ml, icacile, ayinambala
Ulwazi lokhuseleko lweCalycosin
Uphawu:ghs06
Igama lomqondiso:Ingozi
Ingxelo yobungozi:h301
Ingxelo yesilumkiso:P301 + P310
Ikhowudi yeNgozi (eYurophu):t
Ingxelo yoMngcipheko (eYurophu): 25
Ingxelo yoKhuseleko (eYurophu): 45
IKhowudi yoThutho lweeMpahla eziNgozi:UN 3462 6.1 / pgiii
Amasiko eCalycosin
Ikhowudi ye-HS:2914509090
Isishwankathelo saseTshayina:I-HS2914509090 iiketoni eziqulethe amanye amaqela e-oksijini Ixabiso lerhafu eyongeziweyo: 17.0%, irhafu yesaphulelo serhafu: 9.0%, iimeko zokulawula: akukho ntlawulo yeMFN: 5.5%, intlawulo eqhelekileyo: 30.0%
Iimpawu zesibhengezo:igama lemveliso, umxholo wecandelo, injongo, ipakethe yesibhengezo se-acetone
Uncwadi lweCalycosin
Uzinzo lwe-Thermal ye-kudzu root (Pueraria Radix) isoflavones njengezongezo kwiipatties zenkomo.
J. Food Sci.Iteknoloji.52(3), 1578-85, (2015)
Ingcambu ye-Kudzu, i-Pueraria radix, i-extracts yimithombo ecebileyo ye-isoflavones.Olu phononongo luphanda ukuzinza kwe-thermal yePuerar.
I-Calycosin iququzelela imisebenzi ye-Danggui Buxue Tang, i-Chinese herbal decoction eyenza i-Astragali Radix kunye ne-Angelica Sinensis Radix: Uvavanyo ngokusebenzisa i-calycosin-knock out herbal extract.
J.Ethnopharmacol.168 , 150-7, (2015)
I-K.Danggui Buxue Tang (DBT) yi-decoction ye-herbal yaseShayina yakudala equlethe imifuno emibini, i-Astragali Radix (AR) kunye ne-Angelicae Sinensis Radix (ASR), esebenza njengesongezo sokutya sokunyanga abafazi kum...
J. Ethnopharmacol.168 , 150-7, (2015)
I-Danggui Buxue Tang (i-DBT) yi-decoction ye-herbal yakudala yaseTshayina equlethe imifuno emibini, i-Astragali Radix (AR) kunye ne-Angelicae Sinensis Radix (ASR), esebenza njengesongezo sokutya sokunyanga abafazi ...
Iziphumo ezikhuselayo ze-calycosin ngokuchasene ne-CCl4-eyenziwe yokulimala kwesibindi ngokusebenza kwe-FXR kunye ne-STAT3 kwiigundane.
Pharm.Res.32(2), 538-48, (2015)
Ukuphanda umphumo we-hepatoprotective we-calycosin ngokuchasene nokulimala kwesibindi ngokukrakra ngokubambisana ne-FXR activation kunye ne-STAT3 phosphorylation.Imodeli yokulimala kwesibindi enzima yasungulwa yi-intraperi...
IsiNgesi Alias of pistil Calycosin
7,5'-dihydroxy-4'-methoxyisoflavone
4H-1-Benzopyran-4-enye, 7-hydroxy-3-(3-hydroxy-4-methoxyphenyl)-
7,3'-dihydroxy-4'-methoxyisoflavone
7-Hydroxy-3-(3-hydroxy-4-methoxyphenyl)-4H-chromen-4-enye
I-8-hydroxy-3-(3-hydroxy-4-methoxyphenyl)chromen-4-enye
I-3'-hydroxyformononetin
3',7-Dihydroxy-4'-methoxy-isoflavone
Calycosin
3',7-dihydroxy-4'-methoxyisoflavone
7,3'-dihydroxy-4'-methoxyisoflavanon-2-ene
