Esculin;iAesculin;I-Esculoside;I-Bicolorin;Escosyl
Ukusetyenziswa kwe-Esculin
I-Bioflavonoids, i-antioxidant, ikhuthaza umxholo we-vitamin C.
Isenzo sikaEsculin
1. Ukuvuvukala kwe-Anti kunye ne-analgesia: iigundane zafakwa intraperitoneally kunye ne-10mg / kg.I-Carrageenan induced, i-dextrose eyenziwa, i-serotonin induced kunye ne-histamine eyenza "i-arthritis" ibe nemiphumo yokuthintela, kwaye inhibitory inhibitory yayiyi-35,28,20,8% ngokulandelanayo Kwakhona kuxelwe ukuba kunempembelelo yokuthintela kwi-arthritis eyenziwe nge-formaldehyde, kodwa umphumo ibuthathaka kunaleyo ye-carrageenan induced arthritis;I-inhibition ye-dextran arthritis ayibonakali Inokuthintela ukubunjwa kwe-granuloma kwiigundane (indlela yebhola ye-cotton), ukusabela kwe-erythema okubangelwa yimisebe ye-ultraviolet ngasemva kweehagu ze-guinea, kunye nokunyuka kwe-capillary permeability ebangelwa yi-histamine Inomphumo obuthathaka we-analgesic. .
2. Impembelelo kumthamo womchamo kunye ne-uric acid excretion: iindlela ezahlukeneyo zolawulo zinokuphucula ukukhutshwa kwe-uric acid kwiimpuku kunye nemivundla, kwaye ayinayo i-diuretic effect kwiimpuku eziqhelekileyo, kodwa ibe nefuthe elibonakalayo le-diuretic kwiimpuku.
3.Abanye: i-antibacterial, i-anticoagulant kunye ne-inhibiting aldose reductase kwi-lens yegundane.
Igama likaEsculin
Igama lesiNgesi: esculin
Igama lesiTshayina: Heptachlor hemihydrate |heptachlor hemihydrate |6-( β- D-glucopyranoxy) - 7-hydroxy-2h-1-benzofuran-2-enye |aescin |ihashe chestnut ixolo glycoside |ixolo le-chestnut glycoside Isixhenxe samagqabi umoya Aescin |Qiyeling |ixolo le-chestnut glycoside |aescin |6 - (beta-d-glucopyranoxy) - 7-hydroxy-2h-1-benzofuran-2-enye
I-Bioactivity ye-Esculin
Inkcazo: i-esculin yi-fluorescent coumarin glucoside, eyona nxalenye esebenzayo ye-gray bark.I-Esculin iphucula ukuphazamiseka kwengqondo kwi-nephropathy yesifo seswekile (DN) ngokusebenzisa indlela yokubonisa i-MAPK, kwaye ibeka uxinzelelo lwe-antioxidant kunye nemiphumo echasayo.
Iindidi ezinxulumeneyo: icandelo lophando > > umhlaza
Ithagethi: p38 MAPK
Isalathiso:
[1].Knox K, kunye nabanye.I-Coumarin Glucoside, i-Esculin, ityhila iiNguqu eziKhawulezileyo kwi-Phloem-Transport Velocity kwi-Reply to Environmental Cues.IPhysiol yezityalo.2018 Okt;178(2):795-807.
[2].Ingoma ethi Y, et al.I-Esculin iphucula ukuphazamiseka kwengqondo kwi-nephropathy yovavanyo yesifo sikashukela kwaye yenza uxinzelelo lwe-anti-oxidative kunye nemiphumo yokuchasana nokuvuvukala ngendlela ye-MAPK.UMol Med Rep. 2018 May;17(5):7395-7402.
IiPropati zePhysicochemical ze-Esculin
Ubuninzi: 1.7 ± 0.1 g / cm3
Indawo yokuBilisa: 697.7 ± 55.0 ° C kwi-760 mmHg
Indawo yokunyibilika: 203 ° C
Ifomula yemolekyuli: c15h16o9
Ubunzima beMolekyuli: 358.297
Indawo edanyazayo: 262.8 ± 25.0 ° C
Ubunzima obuchanekileyo: 358.089996
PSA: 358.089996
I-LogP:-1.52
Ukubonakala: powder cream
Uxinzelelo lomphunga: 0.0 ± 2.3 mmHg ku-25 ° C
Refractive Index: 1.689
Iimeko zokuGcina
1 Gcina kwindawo epholileyo, eyomileyo nengena umoya.Zigcine kude nemithombo yokubasa kunye nemithombo yobushushu.Khusela ilanga elithe ngqo.Ukutywinwa kwepakethi.Iya kugcinwa ngokwahlukileyo kwi-acids kunye neekhemikhali ezidliwayo, kwaye ukugcinwa okuxutyiweyo akuvumelekanga.Indawo yokugcina iya kuxhotyiswa ngezinto ezifanelekileyo zokuqulatha ukuvuza.
2. I-Argon igcwele indawo yokugcina etywiniweyo
Ukuzinza: sebenzisa kwaye ugcine ngokwemigaqo ngaphandle kokubola kwaye ugweme ukudibanisa nee-oxides
Ukunyibilika kwamanzi: imodeli enyibilikayo
Ulwakhiwo lweemolekyuli
1. Isalathisi se-Molar refractive: 77.35
2. Umthamo we-Molar (cm3 / mol): 202.6
3. Umthamo othile we-Isotonic (90.2k): 628.5
4. Uxinzelelo lomphezulu (dyne / cm): 92.6
5. I-polarizability (10-24cm3): 30.66
Ulwazi loKhuseleko lwe-Esculin
Ikhowudi yengozi (iYurophu): F, C, Xi
Ingxelo yoMngcipheko (eYurophu): R11
Ingxelo yoKhuseleko (iYurophu): s26-s36 / 37 / 39-s45-s24 / 25
Ikhowudi yezoThutho yempahla eyingozi: UN 2924 3 / PG 2
Wgk eJamani: 3
Inombolo ye-RTECS: dj3085000
Ikhowudi yeCustoms: 2942000000
Esculin Customs
Ikhowudi yeCustoms: 2942000000
Igama lesiNgesi lika-Esculin
Crataegin
7-Hydroxy-2-oxo-2H-chromen-6-yl β-D-glucopyranoside
I-EINECS 208-517-5
ivithamin2
Enallachrome
I-Esculetin 6-β-D-glucoside
IPOLYDROM
Bicolorin
I-Esculetin 6-O-glucoside
Polychrome
7-Hydroxy-2-oxo-2H-chromen-6-yl-β-D-glucopyranoside
IBHAYIKOLONI
7-Hydroxycoumarin-6-yl β-D-Glucopyranoside Sesquihydrate
Esculin
7-Hydroxy-6-{[(2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-2-yl]oxy}-2H-chromen- 2-enye
6-(β-D-Glucopyranosyloxy)-7-hydroxy-2H-1-benzopyran-2-one
I-Esculetin 6-bD-glucoside
2H-1-Benzopyran-2-one, 6-(β-D-glucopyranosyloxy) -7-hydroxy-
I-7-Hydroxy-2-oxo-2H-chromen-6-yl β-D-glucopyranoside hydrate (1:1)
Aesculin
MFCD00006879
I-Esculetin-6-O-glucoside
I-2H-1-Benzopyran-2-enye, i-6- (β-D-glucopyranosyloxy) -7-hydroxy-, i-hydrate (1: 1)
Escosyl
