Isoliquiritin
Ukusetyenziswa kwe-Isoliquiritin
I-Isoliquitin yodwa kwingcambu ye-licorice kwaye inokuthintela i-angiogenesis kunye nokwakhiwa kwe-catheter.I-Isoliquitin nayo inomphumela wokudambisa kunye nomsebenzi we-antifungal.
Isenzo se-Isoliquiritin
I-Isoliquiritin ine-antitussive effect, efana naleyo ye-antidepressants.I-Isoliquiritin, i-glycyrrhizin kunye ne-isoliquirigenin ivimbele indlela exhomekeke kwi-p53 kwaye ibonise i-crosstalk phakathi komsebenzi we-Akt.
Igama le-Isoliquiritin
Igama lesiNgesi: isoliquiritin
I-Bioactivity ye-Isoliquiritin
Inkcazo: i-isoliquitin yodwa kwingcambu ye-licorice kwaye inokuthintela i-angiogenesis kunye nokwakhiwa kwe-catheter.I-Isoliquitin nayo inomphumela wokudambisa kunye nomsebenzi we-antifungal.
Iindidi ezinxulumeneyo: icandelo lophando > > usulelo
Umqondiso indlela > > anti usulelo > > umngundo
Inkalo yophando > > ukudumba / ukunganyangeki
Inkalo yophando > > izifo ze-neurological
Isalathiso:
[1].Kobayashi S, et al.I-Inhibitory effect ye-isoliquiritin, i-compound kwingcambu ye-licorice, kwi-angiogenesis kwi-vivo kunye ne-tube formation in vitro.I-Biol Pharm Bull.1995 Okt;18(10):1382-6.
[2].Wang W, kunye nabanye.Iziphumo ze-Antidepressant-ezifana ne-liquiritin kunye ne-isoliquiritin evela kwi-Glycyrrhiza uralensis kuvavanyo lokuqubha olunyanzelwayo kunye novavanyo lokunqunyanyiswa komsila kwiimpuku.Iprog Neuropsychopharmacol Biol Psychiatry.2008 Jul 1;32(5):1179-84.
[3].ULuo J, kunye nabanye.Umsebenzi we-Antifungal we-Isoliquiritin kunye ne-Inhibitory Effect against Peronophythora litchi Chen ngokusebenzisa iMembrane Damage Mechanism.Iimolekyuli.2016 Feb 19;21(2):237.
Iimpawu zePhysicochemical ye-Isoliquiritin
Ubuninzi: 1.5 ± 0.1 g / cm3
Indawo yokuBilisa: 743.5 ± 60.0 ° C kwi-760 mmHg
Indawo yokunyibilika: 185-186 º C
Ifomula yemolekyuli: c21h22o9
Ubunzima beMolekyuli: 418.394
Indawo edanyazayo: 263.3 ± 26.4 ° C
Ubunzima obuchanekileyo: 418.126373
PSA:156.91000
IlogP:0.76
Uxinzelelo lomphunga: 0.0 ± 2.6 mmHg ku-25 ° C
Refractive Index: 1.707
Igama lesiNgesi le-Isoliquiritin
I-2-Propen-1-one, 1-(2,4-dihydroxyphenyl)-3-[4-(β-D-glucopyranosyloxy)phenyl]-, (2E)-
Isoliquiritin
(E) -1-(2,4-dihydroxyphenyl) -3-[4-[(2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl ]oxyphenyl]prop-2-en-1-one
3-Propen-1-one, 1-(2,4-dihydroxyphenyl)-3-(4-(β-D-glucopyranosyloxy)phenyl)-, (2E)-
4-[(1E)-3-(2,4-Dihydroxyphenyl)-3-oxo-1-propen-1-yl]phenyl β-D-glucopyranoside