Iindaba

Kutshanje, inguqulelo entsha yoLuhlu lwe-Inshurensi yezoNyango yeSizwe yakhutshwa, yongeza iindidi ezintsha ezili-148, kubandakanywa amayeza angama-47 aseNtshona kunye namayeza angama-101 aseTshayina.Inani elitsha lamayeza angama-China angamanye aphindwe kabini kunamayeza aseNtshona.Inani lamayeza aseTshayina kunye namayeza aseNtshona kwikhathalogu ye-inshurensi yezonyango iyafana okokuqala.Uqinisekiso lwelizwe lwamayeza elungelo elilodwa lomenzi waseTshayina kunye nenkxaso yawo yophuhliso.Kodwa kwangaxeshanye, amanye amachiza aneziphumo ezingachanekanga zokunyanga kunye nokuxhatshazwa okucacileyo akhutshiwe kuluhlu.Uninzi lwawo ngamayeza aseTshayina.Ke ngoko, ukuze ugweme ukupheliswa yintengiso yamayeza, ukuphuculwa kwamayeza aseTshayina kufuneka kuqaliswe!

Ukuphuhliswa kwamayeza aseTshayina

1. Umgaqo-nkqubo wesizwe uyavumelana nale meko
Kwiminyaka yakutshanje, iinkqubo kunye nemimiselo yelizwe lam amayeza emveli ziye zapapashwa rhoqo, kwaye ziye zaphuculwa ngokuqhubekayo kwaye zaphuculwa, zibonelela ngoyilo oluphezulu oluphezulu kunye nesikhokelo sophuhliso lwexesha elide loshishino lwamayeza emveli aseTshayina.
Inkqubo yokwenziwa ngokusemthethweni kwamayeza aseTshayina ibonisa ukuzimisela kunye namandla elizwe lam ukuxhasa nokukhuthaza uphuhliso lwamayeza aseTshayina.Urhulumente usebenzisa izenzo zokuqinisekisa uluntu kunye namashishini ukuba amayeza emveli aseTshayina, ubutyebi obuxabisekileyo besizwe saseTshayina, buya kuqhutyelwa phambili ngcono ukuze kuxhamle inkitha yabantu.

2. Uphando olwenziweyo lusemnyango
Ukusukela ngo-2017, amaphondo ahlukeneyo akhuphe ngokulandelelana izaziso zokuyeka okanye ukuguqula amayeza ancedisayo ahlukeneyo, eyona njongo iphambili ikukunciphisa imirhumo, kwaye kugxilwe ekubekeni iliso kumachiza aneziphumo ezingachanekanga zokunyanga, iidosi ezinkulu, okanye amaxabiso abizayo.

NgoMatshi walo nyaka, iyeza lokuqala elisekelwe kubungqina behlabathi kumayeza emveli aseTshayina lasekwa.Iziko liya kubonelela ngobungqina bokusebenza kunye nokhuseleko lwamayeza esintu aseTshayina.Ukuba ukuqheleka kweyeza elisekelwe kubungqina kunye namayeza emveli aseTshayina anokudityaniswa ngokwendalo kwimeko yokusebenza, ayizukuphucula kakhulu kuphela inqanaba lokuxilongwa kwezonyango kunye nonyango, kodwa ikwangqina ixabiso leyeza lamayeza emveli aseTshayina kunye nenqanaba phakathi kwehlabathi. inkqubo yenzululwazi ibala lonikezelo kunye namathuba.

NgoJulayi, iKomishoni yezeMpilo yeSizwe yakhupha "Isaziso sokuShicilela kunye nokusasaza iBatch yokuQala yoLuhlu oluPhambili lweMichiza yeSizwe (Amachiza eMichiza kunye neeMveliso ze-Biological) zokuHlola okuPhambili kokuSetyenziswa okuPhambili".Isaziso sesona siyingozi kakhulu ekusebenziseni amayeza e-patent yaseTshayina.Iyeza laseNtshona alikwazi ukumisela amayeza aseTshayina.Iyeza lelungelo elilodwa lomenzi wechiza, eli nyathelo alikokuthintelwa kusetyenziso lwamayeza aseTshayina, kodwa kukulawula ukusetyenziswa kwamayeza obunini aseTshayina.

Phantsi kweemeko ezinje, ukuba amayeza aseTshayina anelungelo lokuncedisa amayeza asekwe kubungqina, aphule imiqobo phakathi kweyeza lesiNtu laseTshayina kunye namayeza asentshona, kwaye angenise izikhokelo zonyango kunye nokuvumelana, kunokuncedisa amayeza aseTshayina ukuba aphule imeko kakuhle!

Ngaphantsi kwemeko entsha ye "Ibhanti enye yeNdlela", ukuthengiswa kwamanye amazwe amayeza aseTshayina kunamandla amakhulu
Ngo-2015, uNksz Tu Youyou waphumelela iBhaso leNobel kwiPhysiology okanye iMedicine ngokuyilwa kwe-artemisinin, eyandisa impembelelo yamayeza aseTshayina phesheya kolwandle.Nangona iyeza laseTshayina lenze igalelo elibalaseleyo kuphuhliso lwamayeza ehlabathi, ukwenziwa kwamayeza aseTshayina kumazwe ngamazwe kusajongene nobunzima obuninzi njengenkcubeko kunye nemigangatho yobugcisa.

Eyokuqala yingxaki yenkcubeko yezonyango.Unyango lwe-TCM lugxininisa ukuhlukana kwe-syndrome kunye nonyango, oluphatha izifo ngokuhlalutya kunye nokulungelelaniswa komzimba womntu;ngelixa iyeza laseNtshona lijolise kwiintlobo zezifo ezilula kunye nonyango lwendawo, kwaye lubaphelise ngokufumana unobangela wesifo.Okwesibini ubunzima bemigangatho yobugcisa.Iyeza laseNtshona liqwalasela ubunye, ukuchaneka kunye nedatha.Ukwamkelwa kwamayeza kusekelwe kwiimfuno zokhuseleko lwamachiza kunye nokusebenza ngempumelelo.Ii-arhente zolawulo lwamayeza eNtshona zikwandulula imigangatho ehambelanayo yokwamkelwa kumayeza aseTshayina.Nangona kunjalo, uninzi lwamayeza aseTshayina ngoku akwilizwe lam.Uphando kunye nophuhliso lwahlala kuphela kwinqanaba lokuphononongwa elibi, i-GLP ehambelanayo kunye ne-GCP azizange zisekwe, kwaye uvavanyo lwezonyango oluxhaswa yidatha yesayensi efunyenwe kulingo lwezonyango lwalungekho.Ukongeza, ukhuphiswano lwentengiso yezizwe ngezizwe luye lwazisa imiceli mngeni enzima kwishishini lamayeza aseTshayina, kwaye ukuphakama kobunzima obahlukeneyo kukhokelele ekucothiseni ukwenziwa kwamayeza aseTshayina kumazwe ngamazwe.

Ngo-2015, ilizwe lam likhuphe "Umbono kunye neZenzo zokuKhuthaza uLwakhiwo oluHlangeneyo lweSilk Road ye-Economic Belt kunye ne-21st Century Maritime Silk Road".Umgaqo-nkqubo wesizwe othi "One Belt One Road" wandululwa ngokusesikweni.Le "yiNdlela entsha yeSilika" yokwenziwa kweshishini lelizwe lam kumazwe ngamazwe kwaye ikhuthaza uphuhliso loqoqosho lwelizwe lam lungene kwinqanaba eliphezulu.amayeza emveli aseTshayina elizwe lam athatha inxaxheba kulwakhiwo lwe “Belt and Road”.Ngesicwangciso somgaqo-nkqubo we "Going Global" yenkcubeko yamayeza aseTshayina, ikhuthaza ilifa kunye nokuveliswa kwamayeza aseTshayina, kwaye ikhawulezisa ukuhlanganiswa kunye nophuhliso lwengcinga yamayeza aseTshayina kunye nobuchwepheshe bale mihla.Esi sicwangciso sinika amandla angaphakathi kunye namathuba amatsha okuthengiswa kwamanye amazwe amayeza aseTshayina.

Ngokwezibalo ze-China Customs, ngo-2016, iimveliso zamayeza emveli aseTshayina zithunyelwe kumazwe angama-185 kunye nemimandla, kwaye ii-arhente ezifanelekileyo zamazwe asecaleni kwendlela zityikitye izivumelwano zentsebenziswano zamayeza angama-86 kunye nelizwe lam.Izinga lokukhula kweemveliso zamayeza emveli aseTshayina ezithunyelwa ngaphandle likhula ngokuthe ngcembe.Kuyabonakala ukuba phantsi kwemeko entsha ye "Ibhanti enye yeNdlela enye", ukuthengiswa kwamanye amazwe amayeza aseTshayina kuyathembisa!

1.UPhando kuNyaniso lweMveli yamaShayina
Injongo yokuphucula amayeza aseTshayina kukusebenzisa ngokupheleleyo iindlela kunye neendlela zenzululwazi kunye neteknoloji yanamhlanje ngesiseko sokuqhubela phambili iingenelo kunye neempawu zamayeza aseTshayina, nokufunda kwimigangatho yezonyango kunye nemimiselo yezonyango, ukuphanda nokuphuhlisa. Iimveliso zamayeza aseTshayina ezinokungena ngokusemthethweni kwimakethi yamayeza ehlabathi, kunye nokuphucula intengiso yamayeza eTshayina.Ukhuphiswano lwemarike.
Ukuphuculwa kwamayeza emveli aseTshayina yinjineli yenkqubo entsonkothileyo.Ngokwekhonkco lemizi-mveliso, inokwahlulwa ibe ngumlambo (umhlaba/imithombo), i-midstream (ifektri/imveliso) kunye nezantsi (uphando/ikliniki).Okwangoku, ukuhlaziywa kwamayeza emveli aseTshayina akulingani, kubonisa imeko "enzima phakathi kunye nokukhanya kwiiphelo ezimbini".Uphando malunga nokuphuculwa kwamayeza emveli aseTshayina adityaniswe nokusebenza kwezonyango lelona khonkco libuthathaka ixesha elide, kodwa ikwalelona khonkco libalulekileyo kwinkqubo yokuphuculwa kwamayeza emveli aseTshayina.Umxholo ophambili wophando lwangoku kwikhonkco loshishino olusezantsi luyimigqaliselo edibeneyo, kubandakanywa uphando kumacandelo ekhemikhali amayeza emveli aseTshayina, oko kukuthi, uphando malunga nokwakheka kweekhemikhali kunye nophando malunga nomthetho wokuguqulwa kokwakheka ngexesha lokucubungula;uphando kwiteknoloji yokulungiselela amayeza emveli aseTshayina, afana nokuphuculwa, ukuphuculwa kunye nobutsha beteknoloji yemveli.Ukuphuhliswa kweefom zedosi, njl.;uphando lwe-pharmacological yamayeza emveli aseTshayina, oko kukuthi, ukufundwa kweempawu zonyango zemveli kunye ne-pharmacology yovavanyo lwangoku;uvavanyo lwenjongo yokusebenza kweklinikhi.

2.Uphando malunga nezithako zamayeza esintu amayeza aseTshayina
Ngenxa yokuba iikhemikhali eziqulethwe kumayeza aseTshayina kunye neekhompawundi zawo zintsonkothe ​​kakhulu, izinto ezibizwa ngokuba "zizithako ezisebenzayo" ezikhankanyiweyo okanye ezilinganiswe kwimigangatho yomgangatho wangoku wamayeza amaninzi aseTshayina kwaye iikhompawundi zawo ikakhulu zezona zithako ziphambili zeyeza eliphambili okanye ezibizwa ngokuba liyeza. izithako zesalathiso, ezingonelanga.Ubungqina bubonisa ukuba sisithako esisebenzayo.Ukusebenzisa uhlalutyo lwangoku kunye neendlela zokufumanisa kunye netekhnoloji encediswa yikhompyuter ukwenza uvavanyo lwe-high-throughput screening (HTS) kunye neempawu (kubandakanywa nekhemikhali kunye neempawu zebhayoloji) zolwazi olukhulu lwecandelo kumayeza emveli aseTshayina kunye nemimiselo yawo edibeneyo, kunye nokuhlola isiseko sezinto ukusebenza kakuhle kwamayeza emveli aseTshayina luphando lokuphuculwa kwamayeza emveli aseTshayina.Inyathelo eliphambili.Ngokuphuculwa kancinci kwe-HPLC, i-GC-MS, i-LC-MS, kunye neteknoloji yemagnethi yenyukliya, kunye nokuqaliswa okuqhubekayo kweethiyori ezahlukeneyo zokusika kunye neendlela ezifana ne-chemometrics, ithiyori yokuqaphela ipateni, i-metabolomics, i-serum chemistry chemistry, njl. , Kuyenzeka ukuba uqaphele ukuhlukana kwe-intanethi ngexesha elinye kunye nohlalutyo lwamaqela amaninzi eekhompawundi kwiisampuli zamayeza aseTshayina, ukufumana idatha yekhwalithi / yobuninzi kunye nolwazi, kunye nokucacisa isiseko esisebenzayo samayeza aseTshayina kunye nemimiselo edibeneyo.

3. Uphando malunga nokusebenza kunye nendlela yemimiselo ye-herbal compound yaseTshayina
Ukongeza kolu phando lukhankanyiweyo ngasentla kumacandelo ekhompawundi, uphando malunga nokusebenza kunye nendlela yekhompawundi ikwangumxholo wophando oyimfuneko.Ukusebenza kwekhompawundi kuqinisekiswa ngeemodeli zeeseli kunye neemodeli zezilwanyana, ngokusebenzisa i-metabolomics, iproteomics, i-transcriptomics, i-phenomics, kunye ne-genomics.Ukucacisa intsingiselo yenzululwazi yamayeza emveli aseTshayina kunye nokubeka isiseko esiluqilima sezenzululwazi kunyango lwezenzululwazi lwamayeza emveli aseTshayina kunye nokuthengiswa kwamanye amazwe amayeza emveli aseTshayina.

4. Uphando kwi-Translational Medicine yeTraditional Chinese Medicine
Kwinkulungwane yama-21, uphando lweyeza lokuguqulela luyindlela entsha ekuphuhliseni isayensi yobomi yamazwe ngamazwe.Isiphakamiso kunye nokuqhubela phambili kophando lweyeza lokuguqulela lubonelela ngomjelo "oluhlaza" wokudibanisa amayeza, isiseko kunye neklinikhi, kwaye ikwabonelela nethuba elitsha lokuphucula uphando lwamayeza aseTshayina."Umgangatho, umgangatho, iipropathi, ukusebenza kakuhle, kunye nokusetyenziswa" zizinto ezisisiseko zamayeza aseTshayina, ezidityanisiweyo zenza imigangatho edibeneyo yamayeza aseTshayina.Ukuqhuba uphando olujoliswe kwiimfuno zeklinikhi ngokudibanisa "umgangatho-ukusebenza-ukusebenza-ukusetyenziswa" kwamayeza esintu aseTshayina yindlela ebalulekileyo yokwenza amayeza emveli aseTshayina asondele ekliniki ngokukhawuleza.Ikwayimfuno engenakuthintelwa yokuguqulwa kophando lwamayeza emveli aseTshayina kuqheliselo lwezonyango, kwaye ikwayimbuyekezo yophando lwamayeza emveli aseTshayina.Ukubonakaliswa okubalulekileyo kwemodeli yokucinga yasekuqaleni yamayeza aseTshayina, kwaye ke ngoko kunokubaluleka okubalulekileyo kunye nokubaluleka okusebenzayo.

Uphando malunga nokuphuculwa kwamayeza emveli aseTshayina ayingomcimbi wesayensi kuphela, kodwa ukwanxulumene nophuhliso lulonke lweshishini lezamayeza lelizwe lam.Phantsi kwemeko evumayo iyonke yemigaqo-nkqubo yesizwe, uphando malunga nokuphuculwa kwamayeza emveli aseTshayina kunye nokwenziwa kwawo kumazwe ngamazwe kuyafuneka.Ngokuqinisekileyo, ayinakwahlulwa kule nkqubo.Iinzame ezidibeneyo zabo bonke abaphandi bezenzululwazi abaphambili!

Ngokujonga uphando lwenkqubo yala maxesha yamayeza emveli aseTshayina, iPuluo Medicine ishwankathele iseti yezimvo ezitsha nezinokwenzeka zophando:

Okokuqala, sebenzisa iimodeli zezilwanyana zokuqinisekisa ukuphumelela, kwaye unqume imiphumo kunye nokulinganisa ngokusebenzisa izikhombisi ezinxulumene nesifo;okwesibini, sebenzisa i-compound-target-pathway prediction based on network pharmacology, sebenzisa i-metabolomics, i-proteomics, i-transcriptomics, kunye ne-phenotypes, uphando lwe-Genomics ukuqikelela isalathiso / inkqubo yokulawulwa kwe-compound;emva koko sebenzisa iimodeli zeeseli kunye nezilwanyana ukufumanisa kunye nokuqinisekisa ulwalathiso lommiselo ngokufumanisa izinto ezivuthayo, uxinzelelo lwe-oxidative, njl., kwaye wenze ukukhangela okujoliswe kuyo ngokufumanisa iimolekyuli zesignali, izinto ezilawulayo, kunye nomxholo ojoliswe kuyo kunye nokuqinisekiswa;Okokugqibela, sebenzisa isigaba solwelo esisebenza kakhulu, i-mass spectrometry, njl.