Orientin
Ukusetyenziswa kwe-Orientin
I-Orientin yi-flavonoid ye-bioactive eyenzeka ngokwemvelo eneempawu ezahlukeneyo zebhayoloji, kuquka i-anti-inflammatory, antioxidant, anti-tumor, ukukhusela intliziyo kunye nokunye.I-Orientin yi-agent ethembisayo ye-neuroprotective, efanelekileyo kunyango lweentlungu ze-neuropathic.
I-Bioactivity ye-Orientin
Inkcazo:I-orientin yi-flavonoid ye-bioactive eyenzeka ngokwemvelo eneempawu ezahlukeneyo zebhayoloji, kuquka i-anti-inflammatory, antioxidant, anti-tumor, ukukhusela intliziyo kunye nokunye.I-Orientin yi-agent ethembisayo ye-neuroprotective, efanelekileyo kunyango lweentlungu ze-neuropathic.
Iindidi ezinxulumeneyo:icandelo lophando > > umhlaza
Indlela yomqondiso > > enye > > enye
Inkalo yophando > > izifo ze-neurological
Rintsingiselo:[1].Dhakal H, et al.Iziphumo ezithintelayo ze-orientin kwi-mast cell-mediated allergic ukudumba.Pharmacol Rep. 2020 Jan 24.
[2].UGuo D, kunye nabanye.I-Orientin kunye neentlungu ze-neuropathic kwiigundane ezine-spinal nerve ligation.61Int Immunopharmacol.2018 May;58:72-79.
IiPropati zePhysicochemical of Orientin
Ubuninzi: 1.8 ± 0.1 g / cm3
Indawo yokuBilisa: 816.1 ± 65.0 ° C kwi-760 mmHg
Indawo yokunyibilika: 260-285 º C
Ifomula yemolekyuli: C21H20O11
Ubunzima beMolekyuli: 448.377
Indawo edanyazayo: 289.1 ± 27.8 ° C
Ubunzima obuchanekileyo: 448.100555
PSA: 201.28000
LogP: 1.58
Ukubonakala: umgubo ophuzi
Uxinzelelo lomphunga: 0.0 ± 3.1 mmHg ku-25 ° C
Refractive Index: 1.767
Ukunyibilika kwamanzi: 1 M
NaOH: i-soluble1mg / ml, icacile, i-orenji etyheli
Ulwazi lokhuseleko lweDigitalis
Ingxelo yoKhuseleko (iYurophu): 24 / 25
Ikhowudi yezothutho yempahla eyingozi: nonh kuzo zonke iindlela zothuthoRTECS号:DJ3009300
Uphononongo loncwadi lwe-Orientin
Ukwahlula i-C-glycosylflavone i-isomer pairs i-orientin / isoorientin kunye ne-vitexin / isovitexin usebenzisa i-HPLC-MS yokulinganisa ubunzima obuchanekileyo kunye ne-CID engaphakathi.
IPhytochem.Impundu.16(5), 295-301, (2005)
I-HPLC-MS isebenzisa i-collision induced dissociation (CID) isetyenziselwe ukuchongwa kwe-C-glycosylflavone i-isomer pairs orientin/isoorientin kunye ne-vitexin/isovitexin.I-HPLC-CID/MS ihlalutya imveliso..
Imiphumo ye-Antihypertensive kunye ne-cardioprotective ye-Lagenaria siceraria isiqhamo kwi-NG-nitro-L-arginine methyl ester (L-NAME) ibangele iigundane ezinoxinzelelo lwegazi.
Pharm.I-Biol.50(11), 1428-35, (2012)
Lagenaria siceraria (Molina) Standl.(Cucurbitacae) (LS) kuye kwabikwa ukuba une-cardioprotective, antihyperlipidemic, kunye nemisebenzi ye-diuretic.Ukuvavanya i-antihypertensive kunye ne-cardioprotective ef ...
Ukuphuhliswa kunye nokuqinisekiswa kwendlela ye-HPTLC yokulinganisa ngaxeshanye i-isoorientin, isovitexin, i-orientin, kunye ne-vitexin kwi-bamboo-leaf flavonoids.
J. AOAC Int.93(5), 1376-83, (2010)
Indlela elula ye-HPTLC iye yaphuhliswa ukumiselwa kwangaxeshanye kwe-isoorientin, isovitexin, i-orientin, kunye ne-vitexin, zombini ezicocekileyo kunye neesampuli zorhwebo ze-bamboo-leaf flavonoids.I-flavon ...
Igama lesiNgesi laseOrientin
(1S) -1,5-Anhydro-1-[2-(3,4-dihydroxyphenyl)-5,7-dihydroxy-4-oxo-4H-chromen-8-yl]-D-glucitol
I-2-(3,4-Dihydroxyphényl) -5,7-dihydroxy-8-[(2S,3R,4R,5S,6R)-3,4,5-trihydroxy-6-(hydroxyméthyl)tétrahydro-2H-pyran- 2-yl]-4H-chromén-4-enye
I-Orientin 8-C-β-D-glucopyranoside
3',4',5,7-tetrahydroxyflavone-8-C-glucoside
I-2-(3,4-Dihydroxyphenyl) -5,7-dihydroxy-8-[(2S,3R,4R,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran- 2-yl] -4H-chromen-4-on
I-Luteolin-8-C-glucoside
3',4',5,7-tetrahydroxyflavone 8-glucoside
I-4H-1-Benzopyran-4-enye, i-2-(3,4-dihydroxyphenyl) -8-β-D-glucopyranosyl-5,7-dihydroxy-
D-Glucitol, 1,5-anhydro-1-C-[2-(3,4-dihydroxyphenyl)-5,7-dihydroxy-4-oxo-4H-1-benzopyran-8-yl]-, (1S) -
Orientin
ilutexin
I-2-(3,4-Dihydroxyphenyl) -5,7-dihydroxy-8-[(2S,3R,4R,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran- 2-yl] -4H-chromen-4-enye
I-2-(3,4-Dihydroxyphenyl) -8-bD-glucopyranosyl-5,7-dihydroxy-4H-1-benzopyran-4-enye
