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Iimveliso

I-Panaxadiol Cas No. 19666-76-3

Inkcazelo emfutshane:

Inombolo yeCas.19666-76-3

I-Panaxadiol lichiza le-antitumor elinoveli elakhelwe kwiginseng.

Umsebenzi webhayoloji wePanaxadiol

Inkcazo:I-Panaxadiol lichiza le-antitumor elinoveli elakhelwe kwiginseng.

Iindidi ezinxulumeneyo:indlela yomqondiso > > enye > > enye

Indawo yophando > > umhlaza

Iimveliso zendalo > > i-terpenoids kunye ne-glycosides


Iinkcukacha zeMveliso

Iithegi zeMveliso

Umsebenzi webhayoloji wePanaxadiol

Inkcazo:I-Panaxadiol lichiza le-antitumor elinoveli elakhelwe kwiginseng.

Iindidi ezinxulumeneyo:indlela yomqondiso > > enye > > enye

Indawo yophando > > umhlaza

Iimveliso zendalo > > i-terpenoids kunye ne-glycosides

Isalathiso:[1].Xiaojun C, et al.Indlela ye-UFLC-MS/MS ye-quantification ye-panaxadiol kwi-rat plasma kunye nokusetyenziswa kwayo kwisifundo se-pharmacokinetic.Planta Med.2013 Sep;79(14):1324-8.

[2].UTae-Hoon Kim, et al.Iziphumo ze-ginseng iyonke i-saponin, i-panaxadiol kunye ne-panaxatriol kwi-ischemia / ukwenzakala kwakhona kwintliziyo yegundane elilodwa.Ukutya kunye ne-Chemicalology ye-ToxicologyVolume 48, iNkupho yesi-6, ngoJuni ka-2010, amaPhepha 1516–1520

IiPropati zePhysicochemical of Panaxadiol

Ubuninzi: 1.0 ± 0.1 g / cm3

Indawo yokuBilisa: 531.3 ± 45.0 ° C kwi-760 mm

I-HgMolecular Formula: C30H52O3

Ubunzima beMolekyuli: 460.732

Indawo eDibanisayo: 275.1 ± 28.7 ° C

Ubunzima obuchanekileyo: 460.391632

PSA: 49.69000

IlogP: 7.64

Uxinzelelo lomphunga: 0.0 ± 3.2 mmHg ku-25 ° C

Refractive Index: 1.515

1. Umlinganiswa: awuqinisekanga

2. Ubuninzi (g / ml, 25 / 4 ℃): akuqinisekanga

3. Ubuninzi bomphunga ohambelanayo (g / ml, umoya = 1): akuqinisekanga

4. Indawo yokunyibilika (º C): 250

5. Indawo yokubila (º C, uxinzelelo lwe-atmospheric): akuqinisekanga

6. Indawo yokubila (º C, 5.2kpa): akuqinisekanga

7. Isalathiso seRefractive: akuqinisekanga

8. Indawo edanyazayo (º C): akuqinisekanga

9. Ukujikeleza okuthe ngqo (º): akuqinisekanga

10. Indawo ezenzekelayo yokutsha okanye ubushushu bokutshisa (º C): akuqinisekanga

11. Uxinzelelo lomphunga (kPa, 25 º C): akuqinisekanga

12. Uxinzelelo lomphunga (kPa, 60 º C): aluqinisekanga

13. Ubushushu bokutsha (kJ / mol): ukungaqiniseki

14. Ubushushu obubalulekileyo (º C): akuqinisekanga

15. Uxinzelelo olunzima (kPa): aluqinisekanga

16. I-Logarithm yamanzi e-oyile (i-octanol / amanzi) i-coefficient yokwahlulahlula: akuqinisekanga

17. Umda wokudubula okuphezulu (%, V / V): akuqinisekanga

18. Umda osezantsi wokudubula (%, V / V): awuqinisekanga

19. Ukunyibilika: ukungaqiniseki

Ukulungiswa kwePanaxadiol

Indlela yamva nje yokulungiselela isicatshulwa se-ginseng ngolu hlobo lulandelayo: I-100g yabantu abaneminyaka emi-5 ukuya kwe-6 ubudala bayatyunyuzwa kwaye baxutywe eludakeni, i-400ml ye-90% ye-ethanol yongezwa, ifakwe kwaye ishukunyiswe imini enye nobusuku, ihluzwe, kunye ne-300ml ye-ethanol. I-90% ye-ethanol yongezwa kwintsalela yokucoca ukukhutshwa kwesibini.Hlanganisa iifilthathi ezimbini kwaye ukhuphe i-ethanol kwi-evaporator, ushiye malunga ne-4G yokugxila.Yongeza i-150ml ye-60% kwi-concentrate, ugxobhoze ukunyibilika, ukucoca kunye nokususa into enganyibilikiyo.Gxininisa i-filtrate ukuya kwi-5-10ml, yongeza i-60ml yamanzi, uyikhuphe nge-80ml ye-ether ngamaxesha angama-3 kwi-funnel eyahlulayo, udibanise i-ether layer, yongeza i-50ml ye-6% yesisombululo se-sodium bicarbonate, xubha ngokupheleleyo, yima ngokubeka, thabatha Umaleko we-ether kwaye uyihlambe ngamanzi adibeneyo ukuze ungathathi hlangothi.Emva koko i-ether isuswa yi-evaporator de i-ether ikhutshwe ngokupheleleyo, kunye ne-extract ginseng efunyenweyo.

IsiNgesi Alias ​​Of Panaxadiol

PALMITIC ACID METHYLESTER(RG) (BONA METHYL PALMITATE)

(3β,12β,20R)-20,25-Epoxydammarane-3,12-diol

Panaxaidol

I-DAMMARANE-3BETA,12BETA-DIOL

I-Dammarane-3,12-diol, 20,25-epoxy-, (3β,12β,20R)-

Panaxadio


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