Platycodin D CAS No. 58479-68-8
Ulwazi oluBalulekileyo
Umthombo wokutsalwa:IPlatycodon grandiflorum (Jacq.) A.DC.Iingcambu ezomileyo.
Imowudi yokubona:I-HPLC ≥ 98%.
Iinkcukacha:20mg, 50mg, 100mg, 500mg, 1g (inokupakishwa ngokweemfuno zabathengi).
Umlinganiswa:Ngumgubo omhlophe wekristale.
Injongo:Isetyenziselwa ukumisela umxholo.
Ilahleko ekomisweni:≤ 2%
Ubunyulu:95%, 98%, 99%
Indlela yohlalutyo:HPLC-DAD ＾ okanye / kunye＾ HPLC-ELSD
Iindlela zokuchonga:i-mass spectrometry (ubunzima), i-nuclear magnetic resonance (NMR)
Ugcino:itywinwe kwaye ikhuselwe ekukhanyeni, -20 ℃.
Ukulumkela:Le mveliso kufuneka igcinwe kwiqondo lokushisa eliphantsi kwaye yome.Iimveliso ezikhethekileyo kufuneka zigcinwe phantsi kwe-nitrogen.Ukuba ayigcinwanga ixesha elide, umxholo uya kuncitshiswa.
Ukunyaniseka:iminyaka eyi-2
Inokuhlangabezana nenani elikhulu leemfuno ngaphezu kwenqanaba legram.Nceda ujonge iinkcukacha.
Ukusebenza kweBioactivity yePlatycodin D
Inkcazo:i-platycodin D yikhompawundi ye-saponin ebekwe yodwa kwisiqu se-orenji, eyi-AMPK α Inomsebenzi wokulwa nokutyeba.
EzinxulumeneyoCamacandelo:indlela yokubonisa > > epigenetics > > AMPK
Indlela yomqondiso > > PI3K / Akt / mTOR indlela yomqondiso > > AMPK
Indawo yophando > > izifo zemetabolism
Ekujoliswe kuko:AMPK α [1]
Iimbekiselo:[1] UKim HL, et al.I-Platycodin D, i-activator yenoveli ye-AMP-activated protein kinase, inciphisa ukutyeba kwi-db / db iimpuku ngolawulo lwe-adipogenesis kunye ne-thermogenesis.IPhytomedicine.2019 Jan;52:254-263 .
IiPropati zePhysicochemical of Platycodin D
Ubuninzi:1.6 ± 0.1 g / cm3
Ifomula yemolekyuli:c57h92o28
Ubunzima bemolekyuli:1225.324
Ubunzima obuchanekileyo:1224.577515
PSA:453.28000
I-LogP:-0.69
Isalathiso seRefractive:1.659
