I-Synephrine
Ukusetyenziswa kweSynephrine
I-Synephrine (i-oxedrine) ithathwe kwizityalo ze-citrus α- Adrenergic kunye ne-β- Adrenergic agonists zineemeko ezifanayo kunye ne-ephedra kunye ne-ephedrine alkaloids.
Igama leSynephrine
Igama lesiNgesi: synephrine
Isibizo saseTshayina: i-deoxyepinephrine |simmforine |DL deoxyepinephrine |I-1-p-hydroxyphenyl-2-methylaminoethanol |Cinephrine |I-1 - (4-hydroxyphenyl) - 2 - (methylamino) ethanol
I-Bioactivity ye-Synephrine
Inkcazo: i-synephrine (i-oxedrine) ithathwe kwizityalo ze-citrus α- Adrenergic kunye ne-β- Adrenergic agonists zineemeko ezifanayo kunye nezakhiwo kunye ne-ephedra kunye ne-ephedrine alkaloids.
Iindidi ezifanelekileyo: i-α-adrenergic kunye ne-β-adrenergic[1]
KwiSifundo seVivo: i-adrenaline (i-1mg / kg; i-gavage yomlomo; ehlala iintsuku ze-8; iigundane ze-PVL kunye ne-BDL) ziphucule kakhulu imeko ye-hyperkinetic ye-PVL kunye ne-BDL.I-PVL kunye neempuku ze-BDL zanciphisa kakhulu uxinzelelo lwe-portal vein, i-portal vein blood flow flow kunye ne-cardiac index, ngelixa unyango lwe-adrenaline lonyuse uxinzelelo lwe-arterial kunye ne-systemic kunye ne-portal vein vascular resistance [2].Imodeli yezilwanyana: Iigundane ezine-portal vein ligation (PVL) okanye i-bile duct ligation (BDL) [2] idosi: 1 mg / kg nganye iiyure ze-12: i-gavage yomlomo;Iziphumo ngosuku lwe-8: iigundane ze-PVL kunye ne-BDL ziye zanciphisa kakhulu uxinzelelo lwe-portal vein, ukuhamba kwegazi kwesebe le-portal kunye nesalathisi senhliziyo, kunye nokwandisa uxinzelelo lwe-arterial kunye ne-systemic kunye ne-portal vein resistance.
Iimbekiselo: 1] Thomas JE, et al.I-STEMI kwindoda eneminyaka eyi-24 emva kokusetyenziswa kwe-synephrine-containing dietary supplement: ingxelo yecala kunye nokuphononongwa kweencwadi.I-Tex Heart Inst J. 2009;36(6):586-90.
[2].Huang YT, et al.Imiphumo ye-Hemodynamic yonyango lwe-synephrine kwiigundane ze-portal hypertensive.Jpn J Pharmacol.2001 Feb;85(2):183-8.
IiPropati zePhysicochemical of Simephrine
Ubuninzi: 1.2 ± 0.1 g / cm3
Indawo yokuBilisa: 341.1 ± 27.0 ° C kwi-760 mmHg
Indawo yokunyibilikisa: 187 ° C (Dec.) (ilayiti.)
Ifomula yemolekyuli: C9H13NO2
Ubunzima beMolekyuli: 167.205
Indawo edanyazayo: 163.4 ± 14.3 ° C
Ubunzima obuchanekileyo: 167.094635
PSA:52.49000
LogP:-0.03
Imbonakalo: imhlophe ukuya kwi-beige powder
Uxinzelelo lomphunga: 0.0 ± 0.8 mmHg ku-25 ° C
Refractive Index: 1.572
Iimeko zokuGcina: Le mveliso kufuneka itywinwe kwaye igcinwe.
Ulwazi ngoKhuseleko lweSynflynn
uphawu: ghs07
Igama lomqondiso: isilumkiso
Ingxelo yengozi: h315-h319-h335
Ingxelo yesilumkiso: p261-p305 + P351 + P338
Izixhobo zokukhusela umntu: uhlobo lwemaski yothuli i-N95 (US);Izikhuselo zamehlo;Iiglavu
Ikhowudi yengozi (eYurophu): Xi: iritant;
Ingxelo yomngcipheko (eYurophu): R36 / 37 / 38
Ingxelo yokhuseleko (eYurophu): s26-s36
Ikhowudi yezothutho yempahla eyingozi: nonh kuzo zonke iindlela zothutho
Inombolo ye-RTECS: do7350000
Ikhowudi yeCustoms: 2922199090
Ukulungiswa kweSynephrine
Iziphumo ze citrus aurantium L.
Izithethe zeSynephrine
Ikhowudi yeCustoms: 29225090
Isishwankathelo saseTshayina: 29225090 Ezinye i-amino alcohol phenols, i-amino acid phenols kunye nezinye iikhompawundi ze-amino ezineoksijini Umlinganiselo we-VAT: 17.0% Izinga lesaphulelo serhafu: 13.0% Iimeko zolawulo: ab.Uluhlu lweerhafu zeMFN: 6.5% Uluhlu lweerhafu ngokubanzi: 30.0%
I-Declaration Elements: igama lemveliso, ukwakheka, umxholo, injongo, i-chroma ye-ethanolamine kunye netyuwa yayo iya kuxelwa, kunye nokupakishwa kwe-ethanolamine kunye netyuwa yayo iya kuxelwa.
Iimeko zokubeka iliso: A. Ifomu yokukhutshwa kwempahla yempahla engena ngaphakathi B. ifomu yokukhutshwa kwempahla ephumayo.
Ukuhlolwa kunye nokuValelwa: R. ulongamelo lwezococeko kunye nokuhlolwa kokutya okuvela kumazwe angaphandle S. ulongamelo lwezococeko kunye nokuhlolwa kokutya okuthunyelwa kwamanye amazwe
Isishwankathelo:2922509090.ezinye i-amino-alcohol-phenols, i-amino-acid-phenols kunye nezinye ii-amino-compounds ezinomsebenzi we-oxygen.IVAT:17.0%.Ireyithi yesaphulelo serhafu:13.0%..Intlawulo yeMFN:6.5%.Uluhlu lweerhafu ngokubanzi: 30.0%
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Igama lesiNgesi leSynephrine
Synefrin
Simpatol
I-EINECS 202-300-9
4-[(1R)-1-Hydroxy-2-(methylamino)ethyl]phenol
(-)-Oxedrine
I-Oxedrine
(-)-Sympatol
(R) -4-(1-hydroxy-2-(methylamino)ethyl)phenol
I-1-(4-Hydroxyphenyl) -2-methylaminoethanol
I-Synephrin
Ethaphene
Analeptin
Simpalon
(-)-Synephrine
I-Benzenemethanol, i-4-hydroxy-α--[(methylamino)methyl]-, (αR)-
I-Synephrine
MFCD00002370
D-Synephrine
(-) -4-hydroxy-α--[(methylamino)methyl]benzenemethanol
I-Sympathol
I-Penterrin
(-)-p-hydroxy-α--[(methylamino)methyl]benzyl utywala
