Vitexin;I-Apigenin8-C-glucoside CAS No. 3681-93-4
Ulwazi oluBalulekileyo
Isifaniso:i-apigenin8-c-glucoside
Igama lomchiza:I-8- β- D-glucopyranosyl-5,7-dihydroxy-2- (4-hydroxyphenyl) -4H-1-benzopyran-4-enye
Ifomula yemolekyuli:c21h20o10 uncumo oluphefumlelweyo: C1 = CC (= CC = C1C2 = CC (= O) C3 = C (O2) C (= C (C = C3O) o) C4C (C (O4) co) o) o) o
Ubunzima bemolekyuli:432.3775
Inombolo yeCAS:3681-93-4
IiPropati zoMzi kunye nezeMichiza
Imbonakalo:umgubo omthubi
Umthombo:ICraeagus pinnatifida, isityalo seRosaceae, sineziqhamo ezomileyo nezivuthiweyo.
Isicelo
Ke ngoko, izinto eziluhlaza zamagqabi acocekileyo eVitex kunye nembewu yeVitex zinqabile, kwaye amagqabi aqokelelweyo eVitex asetyenziselwa ukucoca kunye nokucoca ioyile yeVitex, ekhokelela abavelisi bezityalo ukuba balahle izinto ezisisiseko kwaye bakhuphe iVitexin.Kunoko, basebenzisa amaqabunga e-hawthorn ukukhupha i-Vitexin, i-Vitexin ikhutshwe kwi-flavonoids epheleleyo ye-Hawthorn Leaves ngokusebenzisa i-extraction, ukwahlukana, ukuhlanjululwa kunye nezinye iinkqubo, kwaye ekugqibeleni wenze ukulungiswa okomileyo.
IVitexin isetyenziswa ikakhulu ukunyanga izifo zentliziyo.Ukucoceka kweVitexin ngokuqhelekileyo kuyafuneka ukuba ibe> 98% (HPLC).I-Vitexin ye-injection isetyenziswe kwiyeza zonyango.Imisebenzi ephambili yeVitexin kukukhuthaza ukujikeleza kwegazi kunye nokususa i-stasis yegazi, ukulawula i-qi kunye ne-dredging pulse.Isetyenziselwa ukuthintela isifuba okubangelwa yi-blood stasis.Iimpawu ziquka ukuxinana kwesifuba, ukufuthaniselwa, ukuntlitheka kwindawo engaphambili, ukubetha kwentliziyo, ukulibala, isiyezi kunye ne-tinnitus.Isifo senhliziyo, i-angina pectoris, i-hyperlipidemia, ukunikezelwa kwegazi okwaneleyo kwi-cardiac artery kunye nezinye iimpawu.
Izifo zentliziyo kunye ne-cerebrovascular zezona zifo zixhaphakileyo ebantwini, kwaye ziye zaba ngoyena nobangela mkhulu wokufa emhlabeni.Ngokoqikelelo lwe-WHO, izifo zentliziyo kunye ne-cerebrovascular zibangela ubuncinci ukufa kwezigidi ezili-12 kwihlabathi jikelele minyaka le, kwaye ziye zaba lutshaba lokuqala lwempilo yabantu.Iziganeko eziphezulu kunye nokufa kwezifo zentliziyo zikhokela indlela ye-R & D kunye nemveliso.Amachiza e-cardiovascular and cerebrovascular abalelwa kwi-4 yawona machiza ali-10 aphezulu athengiswa kakhulu kwihlabathi ngo-2005. Zininzi iindidi zamayeza elungelo elilodwa lomenzi wamaTshayina okunyanga izifo zentliziyo, kodwa azikho ngaphezu kweentlobo ezintathu (Fuzheng Ningxin, i-Wentong enevumba elimnandi). , ukukhuthaza ukujikeleza kwegazi kunye nokususa i-stasis yegazi).Ukususela kwimeko yokuthengisa kwiimarike zokuthengisa, i-Vitexin kunye nezinye iziyobisi zokukhuthaza ukujikeleza kwegazi kunye nokususa i-stasis yegazi inesimo esihle sokuthengisa.Lelinye lamachiza akhula ngokukhawuleza.Imarike yanda ngokukhawuleza, inamandla amakhulu, umthamo wemarike enkulu kunye nendawo yokhuphiswano olubanzi.
I-Vitexin ikwayinxalenye yeziyobisi zendalo ezichasene nomhlaza kunye ne-anti-tumor.I-Diaz yangaphandle ibike ukuba i-flavonoids efunyenwe kwi-Vitex negundo, efana ne-Vitexin, ibonise i-cytotoxicity ebanzi kwiiseli zomhlaza womntu kwi-bioassay;Massateru et al.Kufunyenwe ukuba i-bauhinin ivimbele ukukhula kweeseli zomhlaza wemiphunga yabantu (PC-12) kunye neeseli zomhlaza wekholoni yomntu (HCT116) kuvavanyo lwe-MTT.
Abaninzi abavelisi bezityalo bavelisa i-Vitexin yezityalo zezityalo.Ukongeza kwi-extract ye-Vitexin, njenge-Vitexin extract kunye ne-hawthorn extract, bonke bavelisa i-Vitexin njengesalathisi esisebenzayo, kwaye iimveliso zithengiswa kubathengi abane-Vitexin njengesalathisi.Isalathisi somxholo weVitexin kwiicatshulwa zeVitex kunye ne-hawthorn ngokusisiseko kuphela malunga ne-5%.
Ndiyakholwa ukuba uye wabona iingxelo ezifanayo malunga ne-anti-cancer kunye ne-anti-cancer ye-Hawthorn: uphando olutshanje lufumene ukuba i-Hawthorn iqulethe i-compound ebizwa ngokuba yi-Vitexin, enempembelelo ye-anti-cancer.I-Nitrosamine kunye ne-aflatoxin zinokubangela ukwenzeka okanye ukwanda komhlaza wokugaya ukutya.Uphononongo lovavanyo lubonisa ukuba i-hawthorn extract ayinakuvimba kuphela i-nitrosamine synthesis, kodwa iphinda ithintele umphumo we-carcinogenic we-aflatoxin.Ngoko ke, abantu abasengozini enkulu yomhlaza wesisu kufuneka bahlale bedla i-hawthorn.Kwizigulane ezinomhlaza, i-hawthorn kunye nerayisi nayo ingasetyenziselwa ukupheka i-porridge kunye kwimeko ye-dyspepsia, engenakunceda kuphela ukugaya, kodwa iphinde idlale indima encedisayo kwi-anti-cancer.
Umxholo wemichiza ye-Vitexin e-Hawthorn ingaphantsi kakhulu kune-Vitexin, kodwa ngenxa yokuba bambalwa abantu abazi ngokwenene kwaye bayayiqonda i-Vitexin ukuba batyebe, i-anti-cancer kunye ne-anti-cancer effect ye-Vitexin ivaliwe ezintabeni!
