I-Calycosin CAS No. 20575-57-9
Ulwazi Olubalulekile
【Igama elivamile】i-pistil isoflavone
【Igama lesiNgisiI-calycosin
【Inombolo ye-CAS.】 20575-57-9
【Amangqamuzana IsisindoIdatha ye-284.263
【Ukuminyana】 1.4 ± 0.1 g / cm3
【Indawo yokubilisa】536.8 ± 50.0 ° C ku-760 mmHg
【Ifomula ye-Molecular】I-C16H12O5
【Indawo encibilikayo】n/A
Ukusetshenziswa kweCalycosin
I-Calycosin iyinhlanganisela yemvelo enemisebenzi ye-antioxidant kanye ne-anti-inflammatory.
I-Bioactivity ye-Calycosin
Incazelo: I-Calycosin iyinhlanganisela yemvelo enemisebenzi ye-antioxidant ne-anti-inflammatory.
Izigaba ezihlobene:
Indlela yesiginali > > enye > > enye
Umkhakha wocwaningo > > umdlavuza
Imikhiqizo yemvelo > > flavonoids
Ireferensi:
[1].UZhou Y, et al.I-Calycosin yenza i-apoptosis kumdlavuza we-ovarian womuntu SKOV3 amaseli ngokuvula ama-caspases kanye namaprotheni omndeni we-Bcl-2.I-Tumor Biol.2015 Feb 12.
[2].Chen J, et al.I-Calycosin ne-genistein zenza i-apoptosis ingasebenzi ngendlela ye-HOTAIR/p-Akt yokusayina kumaseli omdlavuza webele womuntu we-MCF-7.I-Cell Physiol Biochem.2015;35(2):722-8.
[3].Chen J, et al.I-Calycosin icindezela ukukhula kwamangqamuzana omdlavuza webele ngokusebenzisa umthetho oncike ku-ERβ we-IGF-1R, p38 MAPK kanye nezindlela ze-PI3K/Akt.I-PLoS One.2014 Mar 11;9(3):e91245.
[4].Chen J, et al.I-Calycosin ikhuthaza ukwanda kwamaseli e-estrogen receptor-positive ngokusebenzisa ama-estrogen receptors kanye nokusebenza kwe-ERK1/2 ku-vitro kanye ne-vivo.Umdlavuza Lett.2011 Sep 28;308(2):144-51.
Izakhiwo ze-Physicochemical of Calycosin
Ukuminyana:1.4 ± 0.1 g / cm3
Indawo yokubilisa:536.8 ± 50.0 ° C ku-760 mmHg
Ifomula ye-molecular:I-C16H12O5
Isisindo samangqamuzana:284.263
Iphoyinti le-Flash:205.7 ± 23.6 ° C
I-PSA:79.90000
Isisindo esiqondile:284.068481
I-LogP:2.41
Ukubukeka:okumhlophe kuya kokuphuzi ngokukhanyayo
I-Steam Pressure:0.0 ± 1.5 mmHg ku-25 ° C
Inkomba ye-refractive:1.669
Izimo zesitoreji:2-8 ° C
Ukuncibilika kwamanzi:I-methanol: i-soluble1mg / ml, icacile, ayinambala
Ulwazi lokuphepha lwe-Calycosin
Uphawu:awu 06
Igama lesiginali:Ingozi
Isitatimende esiyingozi:h301
Isitatimende sesixwayiso:P301 + P310
Ikhodi Yengozi (Europe):t
Isitatimende Sobungozi (eYurophu): 25
Isitatimende Sokuphepha (eYurophu): 45
Ikhodi Yokuthutha Impahla Eyingozi:UN 3462 6.1 / pgiii
Amasiko eCalycosin
Ikhodi ye-HS:2914509090
Uhlolojikelele lwesiShayina:I-HS2914509090 ama-ketone aqukethe amanye amaqembu omoya-mpilo Inani lentela eyengeziwe: 17.0%, isilinganiso sesaphulelo sentela: 9.0%, izimo zokulawula: ayikho intela ye-MFN: 5.5%, intela evamile: 30.0%
Izici zesimemezelo:igama lomkhiqizo, okuqukethwe kwengxenye, inhloso, iphakheji yesimemezelo se-acetone
Izincwadi ze-Calycosin
Ukuzinza okushisayo kwempande ye-kudzu (Pueraria Radix) isoflavones njengezithasiselo ku-patties yenkomo.
J. Ukudla Sci.Ubuchwepheshe.52(3), 1578-85, (2015)
Impande ye-Kudzu, i-Pueraria radix, izingcaphuno ziwumthombo ocebile wama-isoflavones.Lolu cwaningo luphenya ukuzinza okushisayo kwePuerar.
I-Calycosin ihlela imisebenzi ye-Danggui Buxue Tang, i-Chinese herbal decoction ehlanganisa i-Astragali Radix ne-Angelica Sinensis Radix: Ukuhlola ngokusebenzisa i-calycosin-knock out i-herbal extract.
J.Ethnopharmacol.168 , 150-7, (2015)
I-K.Danggui Buxue Tang (DBT) isiphuzo sekhambi lesiShayina sakudala esiqukethe amakhambi amabili, i-Astragali Radix (AR) ne-Angelicae Sinensis Radix (ASR), esebenza njengesengezo sokudla sokwelapha abesifazane...
J. Ethnopharmacol.168 , 150-7, (2015)
I-Danggui Buxue Tang (DBT) iyisiphuzo samakhambi saseShayina sakudala esiqukethe amakhambi amabili, i-Astragali Radix (AR) ne-Angelicae Sinensis Radix (ASR), esebenza njengesengezo sokudla sokwelapha abesifazane...
Imiphumela yokuvikela ye-calycosin ngokumelene nokulimala kwesibindi okwenziwe yi-CCl4 ngokusebenza kwe-FXR ne-STAT3 kumagundane.
Ikhemisi.I-Res.32(2), 538-48, (2015)
Ukuphenya ngomphumela we-hepatoprotective we-calycosin ngokumelene nokulimala okukhulu kwesibindi ngokuhambisana nokusebenza kwe-FXR kanye ne-STAT3 phosphorylation.Imodeli yokulimala kwesibindi eyingozi yasungulwa yi-intraperi...
Igama lesiNgisi le-pistil Calycosin
7,5'-dihydroxy-4'-methoxyisoflavone
4H-1-Benzopyran-4-one, 7-hydroxy-3-(3-hydroxy-4-methoxyphenyl)-
7,3'-dihydroxy-4'-methoxyisoflavone
7-Hydroxy-3-(3-hydroxy-4-methoxyphenyl)-4H-chromen-4-one
8-hydroxy-3-(3-hydroxy-4-methoxyphenyl)chromen-4-one
3'-hydroxyformononetin
3',7-Dihydroxy-4'-methoxy-isoflavone
I-Calycosin
3',7-dihydroxy-4'-methoxyisoflavone
7,3'-dihydroxy-4'-methoxyisoflavanon-2-ene