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Imikhiqizo

I-Calycosin CAS No. 20575-57-9

Incazelo emfushane:

I-Calycosin; 7,3'-dihydroxy-4'-methoxyisoflavone


Imininingwane Yomkhiqizo

Omaka bomkhiqizo

Ulwazi Olubalulekile

Igama elivamile】i-pistil isoflavone

Igama lesiNgisiI-calycosin

Inombolo ye-CAS.】 20575-57-9

Amangqamuzana IsisindoIdatha ye-284.263

【Ukuminyana】 1.4 ± 0.1 g / cm3

【Indawo yokubilisa】536.8 ± 50.0 ° C ku-760 mmHg

【Ifomula ye-Molecular】I-C16H12O5

【Indawo encibilikayo】n/A

Ukusetshenziswa kweCalycosin

I-Calycosin iyinhlanganisela yemvelo enemisebenzi ye-antioxidant kanye ne-anti-inflammatory.

I-Bioactivity ye-Calycosin

Incazelo: I-Calycosin iyinhlanganisela yemvelo enemisebenzi ye-antioxidant ne-anti-inflammatory.

Izigaba ezihlobene:

Indlela yesiginali > > enye > > enye

Umkhakha wocwaningo > > umdlavuza

Imikhiqizo yemvelo > > flavonoids

Ireferensi:

[1].UZhou Y, et al.I-Calycosin yenza i-apoptosis kumdlavuza we-ovarian womuntu SKOV3 amaseli ngokuvula ama-caspases kanye namaprotheni omndeni we-Bcl-2.I-Tumor Biol.2015 Feb 12.

[2].Chen J, et al.I-Calycosin ne-genistein zenza i-apoptosis ingasebenzi ngendlela ye-HOTAIR/p-Akt yokusayina kumaseli omdlavuza webele womuntu we-MCF-7.I-Cell Physiol Biochem.2015;35(2):722-8.

[3].Chen J, et al.I-Calycosin icindezela ukukhula kwamangqamuzana omdlavuza webele ngokusebenzisa umthetho oncike ku-ERβ we-IGF-1R, p38 MAPK kanye nezindlela ze-PI3K/Akt.I-PLoS One.2014 Mar 11;9(3):e91245.

[4].Chen J, et al.I-Calycosin ikhuthaza ukwanda kwamaseli e-estrogen receptor-positive ngokusebenzisa ama-estrogen receptors kanye nokusebenza kwe-ERK1/2 ku-vitro kanye ne-vivo.Umdlavuza Lett.2011 Sep 28;308(2):144-51.

Izakhiwo ze-Physicochemical of Calycosin

Ukuminyana:1.4 ± 0.1 g / cm3

Indawo yokubilisa:536.8 ± 50.0 ° C ku-760 mmHg

Ifomula ye-molecular:I-C16H12O5

Isisindo samangqamuzana:284.263

Iphoyinti le-Flash:205.7 ± 23.6 ° C

I-PSA:79.90000

Isisindo esiqondile:284.068481

I-LogP:2.41

Ukubukeka:okumhlophe kuya kokuphuzi ngokukhanyayo

I-Steam Pressure:0.0 ± 1.5 mmHg ku-25 ° C

Inkomba ye-refractive:1.669

Izimo zesitoreji:2-8 ° C

Ukuncibilika kwamanzi:I-methanol: i-soluble1mg / ml, icacile, ayinambala

Ulwazi lokuphepha lwe-Calycosin

Uphawu:awu 06

Igama lesiginali:Ingozi

Isitatimende esiyingozi:h301

Isitatimende sesixwayiso:P301 + P310

Ikhodi Yengozi (Europe):t

Isitatimende Sobungozi (eYurophu): 25

Isitatimende Sokuphepha (eYurophu): 45

Ikhodi Yokuthutha Impahla Eyingozi:UN 3462 6.1 / pgiii

Amasiko eCalycosin

Ikhodi ye-HS:2914509090

Uhlolojikelele lwesiShayina:I-HS2914509090 ama-ketone aqukethe amanye amaqembu omoya-mpilo Inani lentela eyengeziwe: 17.0%, isilinganiso sesaphulelo sentela: 9.0%, izimo zokulawula: ayikho intela ye-MFN: 5.5%, intela evamile: 30.0%

Izici zesimemezelo:igama lomkhiqizo, okuqukethwe kwengxenye, inhloso, iphakheji yesimemezelo se-acetone

Izincwadi ze-Calycosin

Ukuzinza okushisayo kwempande ye-kudzu (Pueraria Radix) isoflavones njengezithasiselo ku-patties yenkomo.

J. Ukudla Sci.Ubuchwepheshe.52(3), 1578-85, (2015)

Impande ye-Kudzu, i-Pueraria radix, izingcaphuno ziwumthombo ocebile wama-isoflavones.Lolu cwaningo luphenya ukuzinza okushisayo kwePuerar.

I-Calycosin ihlela imisebenzi ye-Danggui Buxue Tang, i-Chinese herbal decoction ehlanganisa i-Astragali Radix ne-Angelica Sinensis Radix: Ukuhlola ngokusebenzisa i-calycosin-knock out i-herbal extract.

J.Ethnopharmacol.168 , 150-7, (2015)

I-K.Danggui Buxue Tang (DBT) isiphuzo sekhambi lesiShayina sakudala esiqukethe amakhambi amabili, i-Astragali Radix (AR) ne-Angelicae Sinensis Radix (ASR), esebenza njengesengezo sokudla sokwelapha abesifazane...

J. Ethnopharmacol.168 , 150-7, (2015)

I-Danggui Buxue Tang (DBT) iyisiphuzo samakhambi saseShayina sakudala esiqukethe amakhambi amabili, i-Astragali Radix (AR) ne-Angelicae Sinensis Radix (ASR), esebenza njengesengezo sokudla sokwelapha abesifazane...

Imiphumela yokuvikela ye-calycosin ngokumelene nokulimala kwesibindi okwenziwe yi-CCl4 ngokusebenza kwe-FXR ne-STAT3 kumagundane.

Ikhemisi.I-Res.32(2), 538-48, (2015)

Ukuphenya ngomphumela we-hepatoprotective we-calycosin ngokumelene nokulimala okukhulu kwesibindi ngokuhambisana nokusebenza kwe-FXR kanye ne-STAT3 phosphorylation.Imodeli yokulimala kwesibindi eyingozi yasungulwa yi-intraperi...

Igama lesiNgisi le-pistil Calycosin

7,5'-dihydroxy-4'-methoxyisoflavone

4H-1-Benzopyran-4-one, 7-hydroxy-3-(3-hydroxy-4-methoxyphenyl)-

7,3'-dihydroxy-4'-methoxyisoflavone

7-Hydroxy-3-(3-hydroxy-4-methoxyphenyl)-4H-chromen-4-one

8-hydroxy-3-(3-hydroxy-4-methoxyphenyl)chromen-4-one

3'-hydroxyformononetin

3',7-Dihydroxy-4'-methoxy-isoflavone

I-Calycosin

3',7-dihydroxy-4'-methoxyisoflavone

7,3'-dihydroxy-4'-methoxyisoflavanon-2-ene


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