I-Esculin;I-Aesculin;I-Esculoside;I-Bicolorin;I-Escosyl
Ukusetshenziswa kwe-Esculin
I-Bioflavonoids, i-antioxidant, ikhuthaza okuqukethwe kwe-vitamin C.
Isenzo sika-Esculin
1. Ukulwa nokuvuvukala kanye ne-analgesia: amagundane afakwe ngaphakathi kwe-intraperitoneally nge-10mg / kg.I-Carrageenan eyenziwe, i-dextrose eyenziwe, i-serotonin eyenziwe kanye ne-histamine eyenza "i-arthritis" ibe nemiphumela evimbelayo, futhi amandla okuvimbela ayengama-35,28,20,8% ngokulandelana Kuphinde kubikwe ukuthi kunomphumela ovimbelayo ku-arthritis eyenziwe nge-formaldehyde, kodwa umphumela uwukuthi ibuthakathaka kunaleyo ye-carrageenan ebangelwa isifo samathambo;Ukuvinjelwa kwe-dextran arthritis akubonakali Kungavimbela ukwakheka kwe-granuloma kumagundane (indlela yebhola likakotini), ukusabela kwe-erythema okubangelwa imisebe ye-ultraviolet ngemuva kwezingulube ze-Guinea, kanye nokwanda kwe-capillary permeability okubangelwa i-histamine Inomphumela we-analgesic obuthakathaka. .
2. Umthelela kumthamo womchamo kanye nokuphuma kwe-uric acid: imizila ehlukahlukene yokuphatha ingathuthukisa ukuphuma kwe-uric acid kumagundane nonogwaja, futhi ayinawo umphumela wokukhipha isisu kumagundane avamile, kodwa ibe nomthelela omkhulu wokukhipha isisu kumagundane.
3.Okunye: i-antibacterial, i-anticoagulant kanye ne-inhibiting aldose reductase ku-lens yamagundane.
Igama lika-Esculin
Igama lesiNgisi :esculin
Igama lesiShayina: Heptachlor hemihydrate |heptachlor hemihydrate |6-( β- D-glucopyranoxy) - 7-hydroxy-2h-1-benzofuran-2-one |esho |ihhashi le-chestnut bark glycoside |i-chestnut bark glycoside Umoya wamaqabunga ayisikhombisa Aescin |Qiyela |i-chestnut bark glycoside |esho |6 - (beta-d-glucopyranoxy) - 7-hydroxy-2h-1-benzofuran-2-one
I-Bioactivity ye-Esculin
Incazelo: i-esculin iyi-fluorescent coumarin glucoside, eyingxenye ephumelelayo yegxolo elimpunga.I-Esculin ithuthukisa ukukhubazeka kwengqondo ekuhlolweni kwesifo sikashukela (i-DN) ngokusebenzisa indlela yokusayina ye-MAPK, futhi isebenzisa ukucindezeleka kwe-antioxidant kanye nemiphumela elwa nokuvuvukala.
Izigaba Ezihlobene: inkundla yocwaningo > > umdlavuza
Ithagethi: p38 MAPK
Ireferensi:
[1].U-Knox K, et al.I-Coumarin Glucoside, Esculin, Yembula Izinguquko Ezisheshayo Esivinini Se-Phloem-Zokuthutha Ekuphenduleni Izimpawu Zendawo.I-Physiol yezitshalo.2018 Okthoba;178(2):795-807.
[2].Ingoma Y, et al.I-Esculin ithuthukisa ukukhubazeka kwengqondo ekuhlolweni kwe-nephropathy yesifo sikashukela futhi idala ukucindezelwa kwe-anti-oxidative kanye nemiphumela elwa nokuvuvukala ngendlela ye-MAPK.UMol Med Rep. 2018 May;17(5):7395-7402.
Izakhiwo ze-Physicochemical of Esculin
Ukuminyana: 1.7 ± 0.1 g / cm3
Indawo yokubilisa: 697.7 ± 55.0 ° C ku-760 mmHg
Indawo yokuncibilika: 203 ° C
I-Molecular Formula: c15h16o9
Isisindo se-Molecular: 358.297
I-Flash Point: 262.8 ± 25.0 ° C
Isisindo esinembile: 358.089996
I-PSA: 358.089996
I-LogP:-1.52
Ukubukeka: ukhilimu powder
I-Steam Pressure: 0.0 ± 2.3 mmHg ku-25 ° C
Inkomba ye-Refractive: 1.689
Izimo Zokugcina
1 Gcina endaweni epholile, eyomile futhi enomoya omuhle.Gcina kude nemithombo yokushisa neyokushisa.Vikela elangeni eliqondile.Ukuvalwa kwephakheji.Izogcinwa ngokuhlukana nama-acids namakhemikhali adliwayo, futhi ukugcinwa okuxubile akufanele kuvunyelwe.Indawo yokugcina kufanele ifakwe izinto ezifanele ukuqukatha ukuvuza.
2. I-Argon igcwele isitoreji esivaliwe
Ukuzinza: sebenzisa futhi ugcine ngokuya ngokucaciswa ngaphandle kokubola futhi ugweme ukuthintana nama-oxide
Ukunyibilika kwamanzi: imodeli encibilikayo
Isakhiwo samangqamuzana
1. Inkomba ye-Molar refractive: 77.35
2. Ivolumu ye-Molar (cm3 / mol): 202.6
3. Ivolumu eqondile ye-Isotonic (90.2k): 628.5
4. Ukuqina kobuso (dyne / cm): 92.6
5. I-polarizability (10-24cm3): 30.66
Ulwazi Lokuphepha lwe-Esculin
Ikhodi yengozi (iYurophu): F, C, Xi
Isitatimende Sobungozi (eYurophu): R11
Isitatimende Sokuphepha (Europe): s26-s36 / 37 / 39-s45-s24 / 25
Ikhodi Yezokuthutha yezimpahla eziyingozi: UN 2924 3 / PG 2
I-Wgk Germany: 3
Inombolo ye-RTECS: dj3085000
Ikhodi Yempahla: 2942000000
Esculin Customs
Ikhodi Yempahla:2942000000
Igama lesiNgisi lika-Esculin
I-Crataegin
7-Hydroxy-2-oxo-2H-chromen-6-yl β-D-glucopyranoside
I-EINECS 208-517-5
i-vitaminc2
Enallachrome
I-Esculetin 6-β-D-glucoside
I-POLYDROM
I-Bicolorin
I-Esculetin 6-O-glucoside
I-Polychrom
7-Hydroxy-2-oxo-2H-chromen-6-yl-β-D-glucopyranoside
I-BICOLOIN
I-7-Hydroxycoumarin-6-yl β-D-Glucopyranoside Sesquihydrate
Esculin
7-Hydroxy-6-{[(2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-2-yl]oxy}-2H-chromen- 2-okukodwa
6-(β-D-Glucopyranosyloxy)-7-hydroxy-2H-1-benzopyran-2-one
I-Esculetin 6-bD-glucoside
2H-1-Benzopyran-2-one, 6-(β-D-glucopyranosyloxy) -7-hydroxy-
I-7-Hydroxy-2-oxo-2H-chromen-6-yl β-D-glucopyranoside hydrate (1:1)
I-Aesculin
I-MFCD00006879
I-Esculetin-6-O-glucoside
2H-1-Benzopyran-2-one, 6-(β-D-glucopyranosyloxy) -7-hydroxy-, hydrate (1:1)
I-Escosyl
