I-Fraxetin;I-Fraxetol;7,8-Dihydroxy-6-methoxycoumarin CAS No: 574-84-5
Isifinyezo
Isibizo:I-Qinpi Pavilion;I-Fraxinus lactone
Igama lesiNgisi:i-fraxetin;i-fraxetol
Kungokwezinhlanganisela ze-coumarin.I-flake crystal (ethanol), indawo encibilikayo engu-228 ℃, iphenduka ibe phuzi ngo-150 ℃, futhi ibe nsundu lapho incibilika.Kuyi-hydrolyzate ye-aesculin, encibilika ku-ethanol ne-hydrochloric acid aqueous solution, inyibilika kancane emanzini abilayo futhi engancibiliki ku-ether.
Iphuma ku-Fraxinus brngeana DC Bark, amaqabunga odonga lwe-F. floribunda, njll.
Inomphumela we-anti-dysentery bacilli futhi ngokomtholampilo isetshenziselwa ukwelapha isifo sohudo esiyingozi ezinganeni.
Imikhiqizo ihlinzeka nge-fraxetin: Qinpi Pavilion
Amapharamitha womkhiqizo:Inombolo ye-CAS: 574-84-5
Okuqukethwe okusebenzayo (%):98.5%
Isicelo:ukuzimisela kokuqukethwe, i-reagent ye-pharmacological, njll
Ukucaciswa komkhiqizo:10mg, 20mg, 1g
Faka i-fraxetin:I-Qinpiting, eyaziwa nangokuthi iFraxinus lactone
Igama lesiNgisi:i-fraxetin;I-Fraxetol; i-Coumarin, i-7,8-dihydroxy-6-methoxy-
Inombolo ye-CAS:574-84-5
Ukukhishwa kwemvelo okumsulwa, ngemva kokuqinisekiswa kwesakhiwo se-NMR nokutholwa kobumsulwa kwe-HPLC, okuqukethwe kungaphezu kuka-98.5%.
Isibizo sesiShayina:7,8-dihydroxy-6-methoxycoumarin IsiNgisi Igama: 7,8-dihydroxy-6-methoxycoumarin IsiNgisi isibizo: EINECS No.: 209-376-2 ifomula yemolekyuli: c10h8o5 isisindo sengqamuzana: 208.1675inchi: Inchi = 1 / c10h8o5 -14-6-4-5-2-3-7 (11) 15-10 (5) 9 (13) 8 (6) 12 / h2-4,12-13h, 1h3 ukuminyana: 1.508g/cm indawo abilayo : 472 ° C kuphoyinti elikhanyayo elingu-760 mmHg: 196 ° C
Izakhiwo zePhysicochemical Of Fraxetin
Ukuminyana: 1.5 ± 0.1 g / cm3
Indawo yokubilisa: 472.0 ± 45.0 ° C ku-760 mmHg
Indawo encibilikayo: 230-232 ° C
I-Molecular Formula: c10h8o5
Isisindo se-Molecular: 208.167
I-Flash Point: 196.0 ± 22.2 ° C
IMisa Elinembile: 208.037170
I-PSA: 79.90000
I-LogP:0.59
Ukubukeka: ithebhulethi yekristalu ephuzi ngokukhanyayo
Ukuzinza: i-crystal flake ephuzi ngokuphaphathekile, umbala uba mnyama uma ushiselwa, futhi uba Nsundu eduze nendawo yokuncibilika.Incibilika kancane ku-ether nasemanzini abilayoI-crystal flake ephuzi ngokukhanyayo iba mnyama lapho ishiswa, futhi ibe nsundu eduze nendawo encibilikayo.Incibilika kancane ku-ether nasemanzini abilayo,Ibonakala eluhlaza okwesibhakabhaka ngokuluhlaza phambi kwe-ferric chloride.Izinzile ngaphansi kwezinga lokushisa elivamile nokucindezela.
I-Computational Chemistry
1. Inani eliyisethenjwa lesibalo sepharamitha ye-hydrophobic (xlogp): 1.2
2. Inani labanikeli bebhondi ye-hydrogen: 2
3. Inombolo yama-hydrogen bond receptors: 5
4. Inombolo yamabhondi amakhemikhali ashintshayo: 1
5. Inani lama-tautomer: 16
6. I-Topological molecular polarity surface 76
7. Inani lama-athomu asindayo: 15
8. Ukushaja okungaphezulu: 0
9. Ukuba yinkimbinkimbi: 288
10. Inombolo yama-athomu e-isotopic: 0
11. Thola inani lama-atomic stereocenters: 0
12. Inombolo ye-atomic stereocenters engaqinisekile: 0
13. Nquma inani le-chemical bond stereocenters: 0
14. Inombolo ye-stereocenter yebhondi yamakhemikhali engapheli: 0
15. Inombolo yamayunithi ebhondi ehlangene: 1
