I-Liquiritin Apioside
Ukusetshenziswa kwe-Liquiritin Apioside
I-Liquitin apioside iyi-flavone evela ku-licorice, enomphumela we-antitussive.
Igama le-Liquiritin Apioside
Igama lesiShayina:I-Apigenin glycyrrhizin
Igama lesiNgisi:4-[(2S)-7-Hydroxy-4-oxo-3,4-dihydro-2H-chromen-2-yl]phenyl 2-O-[(2S,3R,4R)-3,4-dihydroxy-4 -(hydroxymethyl)tetrahydro-2-furanyl]-β-D-glucopyranoside
I-Bioactivity ye-Apigenin Glycyrrhizin
Incazelo:I-liquitin apioside iyi-flavone evela ku-licorice, enomphumela we-antitussive.
Izigaba ezifanele:
Indlela yesiginali > > enye > > enye
Inkambu yocwaningo > > ukuvuvukala / ukungatheleleki
Ireferensi:
[1].Wei W, et al.I-Liquiritin apioside inciphisa i-laryngeal chemoreflex kodwa hhayi i-mechanoreflex kumaphuphu amagundane.Am J Physiol Lung Cell Mol Physiol.2020 Jan 1;318(1):L89-L97.
Izakhiwo zePhysicochemical Of Liquiritin Apioside
Ukuminyana: 1.6 ± 0.1 g / cm3
Indawo yokubilisa: 904.5 ± 65.0 ° C ku-760 mmHg
I-Molecular Formula: c26h30o13
Isisindo se-Molecular: 550.509
I-Flash Point: 304.4 ± 27.8 ° C
IMisa Elinembile: 550.168640
Inombolo yepholisi: 1.77
I-Steam Pressure: 0.0 ± 0.3 mmHg ku-25 ° C
Inkomba ye-Refractive: 1.704
Ukunyibilika kwamanzi: cishe akuncibiliki (0.072 g / L) (25 º C)
Isibizo sesiNgisi se-Apigenin Glycyrrhizin
[(2S)-7-Hydroxy-4-oxo-3,4-dihydro-2H-chromen-2-yl]phenyl 2-O-[(2S,3R,4R)-3,4-dihydroxy-4-( i-hydroxymethyl)tetrahydro-2-furanyl]-β-D-glucopyranoside
4H-1-Benzopyran-4-one,2,3-dihydro-7-hydroxy-2-[4-[[2-O-[(2S,3R,4R))-tetrahydro-3,4-dihydroxy-4- (i-hydroxymethyl)-2-furanyl]-β-D-glucopyranosyl]oxy]phenyl]-, (2S)-
I-Liquiritin apioside
Isevisi ye-Yongjian
Isevisi eyenziwe ngokwezifiso yezinto zokubhekisela zamakhemikhali zomuthi wendabuko waseShayina
I-Jiangsu Yongjian Pharmaceutical Technology Co., Ltd. ibilokhu yenza ucwaningo oluyisisekelo lwezinto ezisebenzayo zomuthi wendabuko waseShayina iminyaka engaphezu kweyishumi.Kuze kube manje, inkampani yenze ucwaningo olunzulu ngezinhlobo ezingaphezu kwe-100 zemithi yendabuko yaseShayina evame ukusetshenziswa, futhi yakhipha izinkulungwane zezingxenye zamakhemikhali.
Inkampani inabasebenzi abaphezulu be-R & D kanye nemishini yokuhlola nokuhlaziya ephelele embonini, futhi isize amakhulu ezikhungo zocwaningo lwesayensi.Ingakwazi ukuhlangabezana nezidingo zamakhasimende ngokushesha nangempumelelo.
Inqubo yesevisi
Ukuxhumana kwephrojekthi → ukubalwa kwenani nesikhathi sokulethwa → ukuxhumana nezingxoxo phakathi kwezinhlangothi zombili → ukusayinwa kwenkontileka yesevisi → ukuqaliswa kwephrojekthi → ukuhlolwa komkhiqizo (ukunikeza i-NMR, i-HPLC namanye amamephu okuhlola) → ukulethwa komkhiqizo
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Ukuhlukaniswa kokungcola kwezidakamizwa, ukulungiswa kanye nenkonzo yokuqinisekisa isakhiwo
Ukungcola kwezidakamizwa kuhlobene kakhulu nekhwalithi, ukuphepha kanye nokuzinza kwezidakamizwa.Ukulungiswa nokuqinisekiswa kwesakhiwo sokungcola emithini kungasisiza siqonde izindlela zokungcola futhi kunikeze isisekelo sokuthuthukisa inqubo yokukhiqiza.Ngakho-ke, ukulungiswa nokuhlukaniswa kokungcola kubaluleke kakhulu ocwaningweni nasekuthuthukisweni kwezidakamizwa.
Kodwa-ke, okuqukethwe kokungcola emthini kuphansi, umthombo ubanzi, futhi isakhiwo sifana kakhulu nengxenye eyinhloko.Yibuphi ubuchwepheshe obungasetshenziswa ukuhlukanisa nokuhlanza konke ukungcola emthini ngamunye ngamunye futhi ngokushesha?Yiziphi izindlela nezindlela ezisetshenziswayo ukuze kuqinisekiswe ukwakheka kwalokhu kungcola?Lobu ubunzima kanye nenselelo ebhekene namayunithi amaningi emithi, ikakhulukazi amabhizinisi emithi yezitshalo kanye nemithi yobunikazi yamaShayina.
Ngokusekelwe ezidingweni ezinjalo, inkampani yethule izinsiza zokuhlukanisa ukungcola kwezidakamizwa kanye nezinsizakalo zokuhlanza.Ngokuthembela ku-nuclear magnetic resonance, i-mass spectrometry nezinye izinto zokusebenza nobuchwepheshe, inkampani ingakwazi ukubona ngokushesha ukwakheka kwezinhlanganisela ezihlukanisiwe, ukuze ihlangabezane nezidingo zamakhasimende.
Inqubo yesevisi
Ikhasimende lihlinzeka ngedatha yephrojekthi → ukubalwa kwephrojekthi → ukusayina inkontileka yesevisi → ukuqaliswa kwephrojekthi → ukutholwa komkhiqizo nokuqinisekiswa kwesakhiwo (NMR, MS, IR, LCMS / GCMS) → ukulethwa komkhiqizo
Sicela uxhumane ne-Jiangsu Yongjian Service Center ukuze uthole imininingwane
Ucingo: 0523-86885168
Ukuhlolwa kwezilwane ze-SPF
ububanzi bebhizinisi:
1. Ukuphakelwa kwezilwane ezincane
2. Ukumodela izifo zezilwane
3. Ukunikezwa kwephrojekthi yasekolishi
4. Ukuhlolwa kwe-Pharmacodynamic ku-vivo
5. Ukuhlolwa kwe-Pharmacokinetic
6. Isevisi yokuhlola iseli yesimila
Amandla ethu:
1. Gxila ekuhloleni kwangempela
2. Qinisekisa ngokuqinile inqubo
3. Sayina ngokuqinile isivumelwano sobumfihlo
4. Ilabhorethri Yakho ngaphandle kwezixhumanisi eziphakathi nendawo
5. Ithimba lochwepheshe bezobuchwepheshe liqinisekisa ikhwalithi yokuhlola
Indawo yokuhlola ye-SPF, ukuphakelwa komuntu okwabelwe ngokukhethekile, inqubekelaphambili yokuhlola yokulandelela ngesikhathi sangempela
