Methylophiopogonone A
Ukusetshenziswa kwe-Methylophiopogonone A
I-Methylophiopogonone A iyi-isoflavone ehlukanisiwe nempande ye-Ophiopogon japonicas, enomsebenzi wokulwa nokuvuvukala.
Igama likaMethylophiopogonone A
Igama lesiNgisi: methylophiopogonanone A
Isibizo sesiShayina:Methyl Ophiopogon japonicus high flavone a |methyl Ophiopogon japonicus high flavone a |methyl Ophiopogon japonicus high isoflavone a
I-Bioactivity ye-Methylophiopogonone A
Incazelo: I-methylophiopogonone A iyi-isoflavone ehlukanisiwe nempande ye-Ophiopogon japonicas, enomsebenzi wokulwa nokuvuvukala.
Izigaba ezihlobene: indlela yesiginali > > okunye > > okunye
Inkambu yocwaningo > > ukuvuvukala / ukungatheleleki
Izikhombo: [1] Li N, et al.Ama-homoisoflavonoid alwa nokuvuvukala avela ezimpandeni ezishubile ze-Ophiopogon japonicus.I-Fitoterapia.2012 Sep;83(6):1042-5.
I-Physicochemical Properties ye-Methylophiopogonone A
Ukuminyana: 1.454 ± 0.06 g / cm3
Indawo yokubilisa: 573.6 ± 50.0 ° C ku-760 mmHg
I-Molecular Formula: C19H16O6
Isisindo se-molecule: 340.327
Iphoyinti elikhanyayo: 211.3 ± 23.6 ° C
IMisa Elinembile: 340.094696
I-PSA: 89.13000
I-logP:4.09
I-Steam Pressure: 0.0 ± 1.6 mmHg ku-25 ° C
Inkomba ye-refractive: 1.681
Ukunyibilika kwamanzi: okungaxubeki (4.4e-3 g / L) (25 º C)
Isibizo sesiNgisi sika-Methylophiopogonone A
4H-1-Benzopyran-4-one, 3-(1,3-benzodioxol-5-ylmethyl)-5,7-dihydroxy-6,8-dimethyl-
3-(1,3-Benzodioxol-5-ylmethyl) -5,7-dihydroxy-6,8-dimethyl-4H-chromen-4-one
I-Methylophiopogonone-A
Methylophiopogonone A
Isevisi ye-Yongjian
Isevisi Eyenziwe Ngezifiso Yezikhombo Zezinto Zemithi Yendabuko YamaShayina
I-Jiangsu Yongjian Pharmaceutical Technology Co., Ltd. ibambe iqhaza kakhulu ocwaningweni oluyisisekelo lwezinto ezisebenzayo zemithi yendabuko yamaShayina iminyaka engaphezu kweyishumi.Kuze kube manje, inkampani yenze ucwaningo olunzulu ngezinhlobo ezingaphezu kwe-100 zemithi yendabuko yaseShayina evame ukusetshenziswa, futhi yakhipha izinkulungwane zezingxenye zamakhemikhali.
Inkampani inabasebenzi abaphezulu be-R & D kanye nemishini yokuhlola nokuhlaziya ephelele embonini, futhi isize amakhulu ezikhungo zocwaningo lwesayensi.Ingakwazi ukuhlangabezana nezidingo zamakhasimende ngokushesha nangempumelelo
Ukwehlukaniswa Kokungcola Kwezidakamizwa, Isevisi Yokulungiselela kanye Nesakhiwo Sokuqinisekisa
Ukungcola kwezidakamizwa kuhlobene kakhulu nekhwalithi, ukuphepha kanye nokuzinza kwezidakamizwa.Ukulungiswa nokuqinisekiswa kwesakhiwo sokungcola emithini kungasisiza siqonde izindlela zokungcola futhi kunikeze isisekelo sokuthuthukisa inqubo yokukhiqiza.Ngakho-ke, ukulungiswa nokuhlukaniswa kokungcola kubaluleke kakhulu ocwaningweni nasekuthuthukisweni kwezidakamizwa.
Kodwa-ke, okuqukethwe kokungcola emthini kuphansi, umthombo ubanzi, futhi isakhiwo sifana kakhulu nengxenye eyinhloko.Yibuphi ubuchwepheshe obungasetshenziswa ukuhlukanisa nokuhlanza konke ukungcola emthini ngamunye ngamunye futhi ngokushesha?Yiziphi izindlela nezindlela ezisetshenziswayo ukuze kuqinisekiswe ukwakheka kwalokhu kungcola?Lobu ubunzima kanye nenselelo ebhekene namayunithi amaningi emithi, ikakhulukazi amabhizinisi emithi yezitshalo kanye nemithi yobunikazi yamaShayina.
Ngokusekelwe ezidingweni ezinjalo, inkampani yethule izinsiza zokuhlukanisa ukungcola kwezidakamizwa kanye nezinsizakalo zokuhlanza.Ngokuthembela ku-nuclear magnetic resonance, i-mass spectrometry nezinye izinto zokusebenza nobuchwepheshe, inkampani ingakwazi ukubona ngokushesha ukwakheka kwezinhlanganisela ezihlukanisiwe, ukuze ihlangabezane nezidingo zamakhasimende.
I-SPF Animal Experiment
Indawo yokwakhiwa kwendawo yokuhlolwa kwezilwane ingamamitha-skwele ayi-1500, okuhlanganisa namamitha-skwele angama-400 wendawo yokuhlola yezinga le-SPF kanye namamitha-skwele ayi-100 welebhu yeseli yezinga le-P2.Iholwa ososayensi base-China Pharmaceutical University, yakha ithimba lezobuchwepheshe elibalulekile elinenani labantu ababuyayo.Nikeza amamodeli ezilwane ekhwalithi ephezulu, idizayini yokuhlola, amaphrojekthi aphelele kanye nezinye izinsizakalo zocwaningo lwesayensi ye-biomedical, ukufundisa nokuthuthukiswa kwezimboni.
Ububanzi Bebhizinisi
1. Ukuphakelwa kwezilwane ezincane
2. Ukumodela izifo zezilwane
3. Ukunikezwa kwephrojekthi yasekolishi
4. Ukuhlolwa kwe-Pharmacodynamic ku-vivo
5. Ukuhlolwa kwe-Pharmacokinetic
6. Isevisi yokuhlola iseli yesimila
Amandla Ethu
1. Gxila ekuhloleni kwangempela
2. Qinisekisa ngokuqinile inqubo
3. Sayina ngokuqinile isivumelwano sobumfihlo
4. Ilabhorethri Yakho ngaphandle kwezixhumanisi eziphakathi nendawo
5. Ithimba lochwepheshe bezobuchwepheshe liqinisekisa ikhwalithi yokuhlola
Indawo yokuhlola ye-SPF, ukuphakelwa komuntu okwabelwe ngokukhethekile, inqubekelaphambili yokuhlola yokulandelela ngesikhathi sangempela