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I-Panaxadiol Cas No. 19666-76-3

Incazelo emfushane:

Cas No.19666-76-3

I-Panaxadiol iyinoveli yomuthi we-antitumor ehlukanisiwe ne-ginseng.

Umsebenzi webhayoloji wePanaxadiol

Incazelo:I-Panaxadiol iyinoveli yomuthi we-antitumor ehlukanisiwe ne-ginseng.

Izigaba ezihlobene:indlela yesignali > > enye > > enye

Umkhakha wocwaningo > > umdlavuza

Imikhiqizo yemvelo > > ama-terpenoids nama-glycosides


Imininingwane Yomkhiqizo

Omaka bomkhiqizo

Umsebenzi Webhayoloji wePanaxadiol

Incazelo:I-Panaxadiol iyinoveli yomuthi we-antitumor ehlukanisiwe ne-ginseng.

Izigaba ezihlobene:indlela yesignali > > enye > > enye

Umkhakha wocwaningo > > umdlavuza

Imikhiqizo yemvelo > > ama-terpenoids nama-glycosides

Ireferensi:[1].U-Xiaojun C, et al.Indlela ye-UFLC-MS/MS yokulinganisa i-panaxadiol ku-plasma yamagundane kanye nokusetshenziswa kwayo ocwaningweni lwe-pharmacokinetic.Planta Med.2013 Sep;79(14):1324-8.

[2].Tae-Hoon Kim, et al.Imiphumela ye-ginseng isiyonke ye-saponin, i-panaxadiol ne-panaxatriol ekulimaleni kwe-ischemia/ukuphinda kuphindwe enhliziyweni yegundane elingalodwa.I-Food and Chemical ToxicologyVolume 48, Issue 6, June 2010, Amakhasi 1516–1520

Izakhiwo zePhysicochemical Of Panaxadiol

Ukuminyana: 1.0 ± 0.1 g / cm3

Indawo yokubilisa: 531.3 ± 45.0 ° C ku-760 mm

I-HgMolecular Formula: C30H52O3

Isisindo se-molecule: 460.732

I-Flash Point: 275.1 ± 28.7 ° C

IMisa Elinembile: 460.391632

I-PSA: 49.69000

Inombolo yepholisi: 7.64

Umfutho Wokuhwamuka: 0.0 ± 3.2 mmHg ku-25 ° C

Inkomba ye-Refractive: 1.515

1. Umlingiswa: akuqinisekile

2. Ukuminyana (g / ml, 25/4 ℃): akuqinisekile

3. Ukuminyana komhwamuko okuhlobene (g / ml, umoya = 1): akuqinisekile

4. Iphuzu elincibilikayo (º C): 250

5. Iphoyinti lokubilisa (º C, ukucindezela komkhathi): akuqinisekile

6. Iphoyinti lokubilisa (º C, 5.2kpa): akuqinisekile

7. Inkomba ye-refractive: ayiqinisekile

8. Iphoyinti elikhanyayo (º C): akuqinisekile

9. Ukuzungezisa okuqondile (º): akuqinisekile

10. Indawo ezenzakalelayo yokuvutha noma izinga lokushisa lomlilo (º C): akuqinisekile

11. Ukucindezelwa komhwamuko (kPa, 25 º C): akuqinisekile

12. Ukucindezela komhwamuko ogcwele (kPa, 60 º C): akuqinisekile

13. Ukushisa komlilo (kJ / mol): akuqinisekile

14. Izinga lokushisa elibalulekile (º C): aliqinisekile

15. Ukucindezela okubalulekile (kPa): akuqinisekile

16. I-logarithm yamanzi kawoyela (i-octanol / amanzi) i-partition coefficient: akuqinisekile

17. Umkhawulo wokuqhuma okuphezulu (%, V / V): akuqinisekile

18. Umkhawulo wokuqhuma ophansi (%, V / V): akuqinisekile

19. Ukuncibilika: akuqinisekile

Ukulungiswa kwePanaxadiol

Indlela yakamuva yokulungiselela ukukhishwa kwe-ginseng imi kanje: I-100g yabantu abaneminyaka engu-5 ~ 6 ubudala iyachotshozwa futhi igxotshwe odakeni, i-400ml ye-ethanol engu-90% iyengezwa, icwiliswe futhi inyakanyiswe usuku olulodwa nobusuku, ihlungiwe, kanye no-300ml we-ethanol. I-ethanol engu-90% yengezwa endaweni esele yesihlungi ukuze kukhishwe okwesibili.Hlanganisa izihlungi ezimbili bese uhwamulisa i-ethanol ku-evaporator, ushiye cishe i-4G yokugxila.Engeza u-150ml ka-60% ku-concentrate, ugovuze ukuze uncibilike, hlunga futhi ususe into engancibiliki.Gxilisa i-filtrate ku-5-10ml, engeza u-60ml wamanzi, uyikhiphe ngo-80ml we-ether izikhathi ezingu-3 ku-funnel ehlukanisayo, hlanganisa ungqimba lwe-ether, engeza u-50ml we-6% yesisombululo se-sodium bicarbonate, unyakazise ngokugcwele, umele ukubeka, thatha i-ether layer bese uyigeza ngamanzi acwecwe ukuze ungathathi hlangothi.Khona-ke i-ether isuswa nge-evaporator kuze kube yilapho i-ether ichithwa ngokuphelele, kanye nokukhishwa kwe-ginseng okutholiwe.

Igama lesiNgisi lePanaxadiol

PALMITIC ACID METHYLESTER(RG) (BHEKA I-METHYL PALMITATE)

(3β,12β,20R)-20,25-Epoxydammarane-3,12-diol

I-Panaxaidol

I-DAMMARANE-3BETA,12BETA-DIOL

I-Dammarane-3,12-diol, 20,25-epoxy-, (3β,12β,20R)-

I-Panaxadio


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