I-Platycodin D CAS No. 58479-68-8
Ulwazi Olubalulekile
Umthombo wokukhipha:I-Platycodon grandiflorum (Jacq.) A.DC.Izimpande ezomile.
Imodi yokutholwa:I-HPLC ≥ 98%.
Imininingwane:20mg, 50mg, 100mg, 500mg, 1g (ingapakishwa ngokwezidingo zekhasimende).
Umlingiswa:Kuyimpushana emhlophe ecwebezelayo.
Inhloso:Isetshenziselwa ukunquma okuqukethwe.
Ukulahlekelwa ekumisweni:≤ 2%
Ubumsulwa:95%, 98%, 99%
Indlela yokuhlaziya:I-HPLC-DAD ^ noma / kanye^ HPLC-ELSD
Izindlela zokuhlonza:i-mass spectrometry (isisindo), i-nuclear magnetic resonance (NMR)
Isitoreji:ivalwe futhi ivikelwe ekukhanyeni, -20 ℃.
Izinyathelo zokuzivikela:Lo mkhiqizo kufanele ugcinwe ekushiseni okuphansi futhi womile.Imikhiqizo ekhethekile kufanele igcinwe ngaphansi kwe-nitrogen.Uma ingagcinwa isikhathi eside, okuqukethwe kuzoncishiswa.
Ukufaneleka:iminyaka engu-2
Ingakwazi ukuhlangabezana nenani elikhulu lezidingo ezingaphezu kwezinga legram.Sicela uthintane ukuze uthole imininingwane.
I-Bioactivity ye-Platycodin D
Incazelo:i-platycodin D iyinhlanganisela ye-saponin ehlukanisiwe nesiqu esawolintshi, okuyi-AMPK α Inomsebenzi wokulwa nokukhuluphala.
OkuhlobeneCizigaba:indlela yokusayina > > i-epigenetics > > AMPK
Indlela yesiginali > > PI3K / Akt / mTOR indlela yesiginali > > AMPK
Umkhakha wocwaningo > > izifo ze-metabolic
Ithagethi:I-AMPK α [1]
Izithenjwa:[1] UKim HL, et al.I-Platycodin D, i-activator yenoveli ye-AMP-activated protein kinase, inciphisa ukukhuluphala kumagundane e-db/db ngokulawulwa kwe-adipogenesis kanye ne-thermogenesis.I-Phytomedicine.2019 Jan;52:254-263.
I-Physicochemical Properties ye-Platycodin D
Ukuminyana:1.6 ± 0.1 g / cm3
Ifomula ye-molecular:c57h92o28
Isisindo samangqamuzana:1225.324
Isisindo esiqondile:1224.577515
I-PSA:453.28000
I-LogP:-0.69
Inkomba ye-refractive:1.659