I-Synephrine
Ukusetshenziswa kwe-Synephrine
I-Synephrine (i-oxedrine) itholakala ezitshalweni ze-citrus α- Adrenergic kanye ne-β- Adrenergic agonists banokufana okuzwelayo kanye nesakhiwo ne-ephedra ne-ephedrine alkaloids.
Igama le-Synephrine
Igama lesiNgisi: synephrine
Isibizo saseShayina: i-deoxyepinephrine |simfoni |DL deoxyepinephrine |1-p-hydroxyphenyl-2-methylaminoethanol |i-cinephrine |1 - (4-hydroxyphenyl) - 2 - (methylamino) ethanol
I-Bioactivity ye-Synephrine
Incazelo: I-synephrine (i-oxedrine) itholakala ezitshalweni ze-citrus α- Adrenergic kanye ne-β- Adrenergic agonists banokufana okuzwelayo kanye nesakhiwo ne-ephedra ne-ephedrine alkaloids.
Izigaba ezifanele: i-α-adrenergic kanye ne-β-adrenergic[1]
Esifundweni se-Vivo: i-adrenaline (1mg / kg; i-gavage yomlomo; ehlala izinsuku ezingu-8; amagundane e-PVL kanye ne-BDL) yathuthukisa kakhulu isimo se-hyperkinetic samagundane e-PVL kanye ne-BDL.Amagundane e-PVL kanye ne-BDL anciphisa kakhulu ukucindezela kwe-portal vein, ukugeleza kwegazi kwegatsha le-portal vein kanye nenkomba yenhliziyo, kuyilapho ukwelashwa kwe-adrenaline kwanda ukucindezela kwe-arterial kanye ne-systemic kanye ne-portal vein vascular resistance [2].Imodeli yezilwane: Amagundane ane-portal vein ligation (PVL) noma i-bile duct ligation (BDL) [2] umthamo: 1 mg / kg njalo emahoreni ayi-12: i-oral gavage;Imiphumela ngosuku lwe-8: Amagundane e-PVL kanye ne-BDL ayenciphise kakhulu ukucindezeleka kwe-portal vein, ukugeleza kwegazi kwegatsha le-portal kanye nenkomba yenhliziyo, kanye nokwanda kwengcindezi ye-arterial kanye ne-systemic kanye ne-portal vein resistance.
Izikhombo: 1] Thomas JE, et al.I-STEMI kumuntu oneminyaka engu-24 ngemuva kokusetshenziswa kwe-synephrine-containing dietary supplement: umbiko wecala nokubuyekezwa kwezincwadi.I-Tex Heart Inst J. 2009;36(6):586-90.
[2].U-Huang YT, et al.Imiphumela ye-Hemodynamic yokwelashwa kwe-synephrine kumagundane we-portal hypertensive.I-Jpn J Pharmacol.2001 Feb;85(2):183-8.
Izakhiwo zePhysicochemical of Simephrine
Ukuminyana: 1.2 ± 0.1 g / cm3
Indawo yokubilisa: 341.1 ± 27.0 ° C ku-760 mmHg
Iphuzu elincibilikayo: 187 ° C (Dec.) (lit.)
I-Molecular Formula: C9H13NO2
Isisindo se-Molecular: 167.205
Iphoyinti elikhanyayo: 163.4 ± 14.3 ° C
Isisindo esinembile: 167.094635
I-PSA: 52.49000
I-LogP:-0.03
Ukubukeka: kusuka kumhlophe kuya kumpushana we-beige
I-Steam Pressure: 0.0 ± 0.8 mmHg ku-25 ° C
Inkomba ye-Refractive: 1.572
Izimo Zokugcina: Lo mkhiqizo kufanele uvalwe futhi ugcinwe.
Ulwazi Lokuphepha Lwe-Synflynn
Izimpawu: ghs07
Igama lesiginali: isixwayiso
Isitatimende sengozi: h315-h319-h335
Isitatimende sesexwayiso: p261-p305 + P351 + P338
Imishini yokuzivikela yomuntu siqu: uhlobo lwemaski yothuli i-N95 (US);Izihlangu zamehlo;Amagilavu
Ikhodi yengozi (eYurophu): Xi: iritant;
Isitatimende sobungozi (eYurophu): R36 / 37/38
Isitatimende sokuphepha (Europe): s26-s36
Ikhodi yokuthutha yezimpahla eziyingozi: i-nonh yazo zonke izindlela zokuthutha
Inombolo ye-RTECS: do7350000
Ikhodi Yempahla: 2922199090
Ukulungiswa kwe-Synephrine
Imiphumela ye-citrus aurantium L.
I-Synephrine Customs
Ikhodi Yempahla: 29225090
Uhlolojikelele lwaseShayina: 29225090 Amanye ama-amino alcohol phenol, amino acid phenol nezinye izinhlanganisela zama-amino ezinomoya-mpilo Izinga le-VAT: 17.0% Izinga lesaphulelo sentela: 13.0% Izimo zokulawula: ab.Intengo ye-MFN: 6.5% Intengo evamile: 30.0%
I-Declaration Elements: igama lomkhiqizo, ukwakheka, okuqukethwe, inhloso, i-chroma ye-ethanolamine nosawoti wayo kuzobikwa, futhi ukupakishwa kwe-ethanolamine nosawoti wayo kuzobikwa.
Izimo zokugada: A. Ifomu lokuvunyelwa kwempahla yentela Yezimpahla Ezingenayo B. ifomu lemvume yempahla yempahla ephumayo.
Ukuhlolwa kanye Nokuhlukaniswa: R. ukugadwa kwenhlanzeko kanye nokuhlolwa kokudla okuvela kwamanye amazwe S. ukugadwa kwenhlanzeko kanye nokuhlolwa kokudla okuthunyelwa kwamanye amazwe
Isifinyezo:2922509090.amanye ama-amino-alcohol-phenols, amino-acid-phenols namanye ama-amino-compounds anomsebenzi we-oxygen.I-VAT:17.0%.Izinga lesaphulelo sentela:13.0%..Intengo ye-MFN:6.5%.Intengo ejwayelekile:30.0%
I-Synephrine Literature
Iphrofayili ye-Phytochemical kanye nomsebenzi we-antioxidant we-physiological drop of citrus fruit.
J. Ukudla Sci.78(1), C37-42, (2013)
Okuqukethwe kwe-phytochemical kanye nomsebenzi we-antioxidant (AA) wokwehla komzimba wezinhlobo eziyinhloko zamawolintshi ezitshalwa eShayina kuye kwaphenywa.Phakathi kwama-flavonoids, i-hesperidin yatholakala ikakhulukazi emandleni ...
Ukuhlaziywa ngesikhathi esisodwa kwezikhuthazi zohlobo lwe-amphetamine ku-plasma nge-solid-phase microextraction kanye ne-gas chromatography-mass spectrometry.
J. Anal.I-Toxicol.38(7), 432-7, (2014)
I-Brazil ibhekwa njengelinye lamazwe anenani eliphezulu kakhulu labasebenzisi be-amphetamine-type stimulant (ATS) emhlabeni wonke, ikakhulukazi i-diethylpropion (DIE) ne-fenproporex (FEN).Ukusetshenziswa kwe-ATS ikakhulukazi kuxhumene..
I-in situ synthesis ye-homochiral metal-organic framework kukholamu ye-capillary ye-capillary electrochromatography enantioseparation.
J. Chromatogr.A. 1388 , 207-16, (2015)
I-Homochiral metal-organic frameworks (MOFs) ithembisa njengesigaba esimile esinezimbotshana sokuhlukaniswa kwe-open-tubular capillary electrochromatography (OT-CEC) ngenxa yosayizi bazo bezimbotshana ezishunwe kahle...
Igama lesiNgisi elithi Synephrine
I-Synefrin
I-Simpatol
I-EINECS 202-300-9
4-[(1R)-1-Hydroxy-2-(methylamino)ethyl]phenol
(-) -Oxedrine
I-Oxedrine
(-)-Sympatol
(R) -4-(1-hydroxy-2-(methylamino)ethyl)phenol
I-1-(4-Hydroxyphenyl) -2-methylaminoethanol
I-Synephrin
I-Ethaphene
I-Analeptin
Simpalon
(-)-Synephrine
I-Benzenemethanol, i-4-hydroxy-α--[(methylamino)methyl]-, (αR)-
I-Synephrine
I-MFCD00002370
I-D-Synephrine
(-) -4-hydroxy-α--[(methylamino)methyl]benzenemethanol
I-Sympathol
I-Penterrin
(-)-p-hydroxy-α--[(methylamino)methyl]benzyl utshwala
