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Imikhiqizo

I-Vitexin;I-Apigenin8-C-glucoside CAS No. 3681-93-4

Incazelo emfushane:

I-Vitexin iyi-flavonoid yemvelo ekhishwe emaqabunga e-Vitex kanye nembewu ye-Vitex.Kodwa-ke, ngenxa yokuthi isitshalo se-Vitex sisesendle, sivamile ezindaweni eziseningizimu yezintaba kodwa sikhula sihlakazekile.Kukhona i-Vitex yokwenziwa embalwa, futhi cishe akukho ukutshalwa kwangempela kwe-Vitex okukhulu.Amaqabunga kanye nembewu ye-Vitex trifolia eqoqwe ngezinto ezivamile zokwelapha zaseShayina zonke ziqoqwa ndawonye namaqabunga nembewu ye-Vitex trifolia, i-Vitex trifolia ne-Vitex trifolia.Akulona uhlobo olulodwa lwe-Vitex trifolia.


Imininingwane Yomkhiqizo

Omaka bomkhiqizo

Ulwazi Olubalulekile

Isibizo:i-apigenin8-c-glucoside

Igama lekhemikhali:8- β- D-glucopyranosyl-5,7-dihydroxy-2-(4-hydroxyphenyl) -4H-1-benzopyran-4-one

Ifomula ye-molecular:c21h20o10 ukumamatheka kwecanonical: C1 = CC (= CC = C1C2 = CC (= O) C3 = C (O2) C (= C (C = C3O) o) C4C (C (C (O4) co) o) o) o

Isisindo samangqamuzana:432.3775

Inombolo ye-CAS:3681-93-4

Izakhiwo Zomzimba Nezamakhemikhali

Ukubukeka:impushana ephuzi

Umthombo:I-Craeagus pinnatifida, isitshalo se-Rosaceae, sinezithelo ezomile nezivuthiwe.

Isicelo

Ngakho-ke, izinto zokusetshenziswa zamaqabunga e-Vitex ahlanzekile kanye nembewu ye-Vitex ayitholakali kalula, futhi amaqabunga e-Vitex aqoqiwe asetshenziselwa ukucwenga kanye nokucwenga uwoyela we-Vitex, okuholela abakhiqizi besizinda sesitshalo ukuthi balahle izinto eziyisisekelo futhi bakhiphe i-Vitexin.Esikhundleni salokho, basebenzisa amaqabunga e-hawthorn ukuze bakhiphe i-Vitexin, bakhiphe i-Vitexin ku-flavonoids ephelele ye-Hawthorn Leaves ngokusebenzisa isizinda, ukuhlukaniswa, ukuhlanzwa nezinye izinqubo, futhi ekugcineni benze ukulungiswa okufriziwe.

I-Vitexin isetshenziselwa ikakhulukazi ukwelapha izifo zenhliziyo.Ubumsulwa beVitexin ngokuvamile budingeka ukuthi bube > 98% (HPLC).I-Vitexin yomjovo isetshenziswe emithini yomtholampilo.Imisebenzi esemqoka ye-Vitexin ukukhuthaza ukujikeleza kwegazi nokususa ukuqina kwegazi, ukulawula i-qi kanye nokudonsa ishayela.Isetshenziselwa ukuvimbela isifuba okubangelwa ukusimama kwegazi.Izimpawu zihlanganisa ukucinana kwesifuba, ukuminwa, ukuntweza endaweni engaphambi kokuphuma kwegazi, ukushaya kwenhliziyo, ukukhohlwa, isiyezi kanye ne-tinnitus.Isifo senhliziyo, i-angina pectoris, i-hyperlipidemia, ukutholakala kwegazi okwanele komthambo wenhliziyo nezinye izimpawu.

Izifo zenhliziyo kanye ne-cerebrovascular yizifo ezivame kakhulu kubantu, futhi seziyimbangela enkulu yokufa kwabantu emhlabeni.Ngokwezilinganiso ze-WHO, izifo zenhliziyo nemithambo yegazi zibangela ukufa okungenani kwezigidi ezingu-12 emhlabeni wonke minyaka yonke, futhi seziphenduke isitha sokuqala sempilo yabantu.Izehlakalo eziphezulu nokufa kwezifo zenhliziyo ziqondisa indlela yomuthi i-R & D nokukhiqizwa.Izidakamizwa zenhliziyo nemithambo yegazi zibalwe emithini emi-4 kweyi-10 ethengwa kakhulu emhlabeni ngo-2005. Kunezinhlobo eziningi zemithi yobunikazi yamaShayina yokwelapha izifo zenhliziyo nemithambo yegazi, kodwa azikho izinhlobo ezingaphezu kwezintathu (i-Fuzheng Ningxin, i-Wentong enuka kamnandi. , ukukhuthaza ukujikeleza kwegazi nokususa i-stasis yegazi).Kusukela esimweni sokuthengisa emakethe yokudayisa, i-Vitexin nezinye izidakamizwa zokukhuthaza ukujikeleza kwegazi nokususa i-blood stasis zinesimo esihle sokuthengisa.Ingenye yezidakamizwa ezikhula ngokushesha.Imakethe ikhula ngokushesha, inamandla amakhulu, amandla emakethe amakhulu kanye nendawo yokuncintisana ebanzi.

I-Vitexin iphinde ibe ingxenye yezidakamizwa zemvelo zokulwa nomdlavuza kanye ne-anti-tumor.I-Diaz yangaphandle ibike ukuthi ama-flavonoid atholakala ku-Vitex negundo, njenge-Vitexin, abonise i-cytotoxicity eningi kumaseli omdlavuza womuntu ku-bioassay;Massateru et al.Kutholwe ukuthi i-bauhinin ivimbele ukukhula kwamangqamuzana omdlavuza wamaphaphu womuntu (PC-12) namaseli omdlavuza wekoloni lomuntu (HCT116) ekuhlolweni kwe-MTT.

Abakhiqizi abaningi bezitshalo zezitshalo bakhiqiza izitshalo zezitshalo ze-Vitexin.Ngaphezu kokukhishwa kwe-Vitexin, okufana ne-Vitexin ekhishwe kanye ne-hawthorn ekhishwe, bonke bakhiqiza i-Vitexin njengenkomba yengxenye esebenzayo, futhi imikhiqizo ibuye ithengiswe kumakhasimende ane-Vitexin njengenkomba.Inkomba yokuqukethwe kwe-Vitexin ekukhishweni kwe-Vitex ne-hawthorn ngokuyisisekelo icishe ibe ngu-5%.

Ngikholelwa ukuthi uke wabona imibiko efanayo mayelana ne-anti-cancer kanye ne-anti-cancer ye-Hawthorn: izifundo zamuva zithole ukuthi i-Hawthorn iqukethe i-compound ebizwa ngokuthi i-Vitexin, enomphumela wokulwa nomdlavuza.I-Nitrosamine ne-aflatoxin kungabangela ukwenzeka noma ukwanda komdlavuza wokugaya ukudla.Ucwaningo lokuhlola lubonisa ukuthi ukukhishwa kwe-hawthorn akukwazi nje ukuvimba ukuhlanganiswa kwe-nitrosamine, kodwa futhi kuvimbela umphumela we-carcinogenic we-aflatoxin.Ngakho-ke, abantu abasengozini enkulu yomdlavuza wesisu kufanele bavame ukudla i-hawthorn.Ezigulini ezinomdlavuza, i-hawthorn nelayisi ingasetshenziswa futhi ukupheka iphalishi ndawonye uma kwenzeka i-dyspepsia, engakwazi ukusiza ukugaya kuphela, kodwa futhi idlale indima eyisizayo ekulweni nomdlavuza.

Okuqukethwe kwamakhemikhali e-Vitexin e-Hawthorn kuncane kakhulu kunaleyo ye-Vitexin, kodwa ngenxa yokuthi bambalwa abantu abazi ngempela futhi abayiqondayo i-Vitexin ukuze bacebe, umphumela wokulwa nomdlavuza kanye nokulwa nomdlavuza we-Vitexin uvalelwe ezintabeni!


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